Pantoprazole 40mg + Domperidone 30mg Gastro-resistant and SR Capsules

Pantoprazole 40mg + Domperidone 30mg combines a proton-pump inhibitor with a prokinetic medicine for selected reflux symptoms associated with nausea or impaired upper-gut motility. It addresses acid-related irritation and movement of stomach contents through different mechanisms.
Take before a meal, usually about 30 minutes before breakfast. Swallow the capsule whole without crushing the gastro-resistant or sustained-release contents. The domperidone component makes this different from routine long-term pantoprazole-only treatment.
Pantoprazole blocks the gastric proton pump and reduces acid secretion. Domperidone blocks peripheral dopamine receptors, promoting upper gastrointestinal motility and reducing nausea.
Headache, diarrhoea, abdominal discomfort, dry mouth and raised prolactin-related symptoms can occur. Fainting, palpitations or an irregular heartbeat requires urgent assessment.
Domperidone can prolong the QT interval, especially with electrolyte abnormalities, heart disease or interacting medicines. Strong CYP3A4 inhibitors can increase risk. Difficulty swallowing, gastrointestinal bleeding or unexplained weight loss needs investigation rather than symptom suppression alone.
Combines acid suppression and prokinetic action when both are needed for the presenting reflux-related symptoms.
No. It also contains sustained-release domperidone, which adds motility effects and separate cardiac precautions.
Pantoprazole suppresses acid production over time; it is not an instant neutralising antacid.
Pre-meal dosing helps pantoprazole act when meal-stimulated acid pumps become active.
Some of these medicines raise domperidone exposure or prolong QT, increasing arrhythmia risk.
No. The prokinetic component is useful only when its additional role fits the patient's symptoms and risk profile.
PPI: proton-pump inhibitor. Prokinetic: a medicine that promotes gastrointestinal movement. GORD: gastro-oesophageal reflux disease. Prolactin: a hormone that can rise with dopamine-blocking medicines; AR: Pantoprazole 40mg + Domperidone 30mg كبسولات معوية وممتدة التحرر; FR: Pantoprazole 40mg + Domperidone 30mg gélules gastro-résistantes et à libération prolongée; PT: Pantoprazole 40mg + Domperidone 30mg cápsulas gastrorresistentes e de libertação prolongada; ES: Pantoprazole 40mg + Domperidone 30mg cápsulas gastrorresistentes y de liberación prolongada; RU: Pantoprazole 40mg + Domperidone 30mg кишечнорастворимые капсулы с пролонгированным высвобождением; ID: Pantoprazole 40mg + Domperidone 30mg kapsul salut enterik dan lepas lambat; VI: Pantoprazole 40mg + Domperidone 30mg viên nang bao tan trong ruột và giải phóng kéo dài; MS: Pantoprazole 40mg + Domperidone 30mg kapsul bersalut enterik dan pelepasan berpanjangan; TL: Pantoprazole 40mg + Domperidone 30mg kapsulang may enterikong balot at matagal na paglabas; ZH-SG: Pantoprazole 40mg + Domperidone 30mg 肠溶及缓释胶囊
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Pantoprazole 40mg + Domperidone 30mg Gastro-resistant and SR Capsules