Adrenaline (Epinephrine) 1mg/mL

Product Introduction

Adrenaline (Epinephrine) 1mg/mL is an emergency injectable medicine containing adrenaline, also called epinephrine. It is used in life-threatening situations such as severe allergic reactions, anaphylaxis, cardiac arrest, and dangerously low blood pressure or shock where adrenaline is clinically indicated.

How to use

Adrenaline (Epinephrine) 1mg/mL is administered according to the emergency indication. In anaphylaxis, adrenaline is commonly given intramuscularly into the outer thigh; in cardiac arrest or critical-care shock, different IV routes and dilutions may be used by trained professionals. Monitoring may include pulse, blood pressure, breathing, oxygenation, ECG, and response to resuscitation.

How it works

Adrenaline activates alpha and beta adrenergic receptors. Alpha activity tightens blood vessels and raises blood pressure. Beta-1 activity supports heart rate and contraction. Beta-2 activity relaxes airway smooth muscle and helps reduce wheeze and breathing difficulty in severe allergic reactions.

Common side effects

Possible effects include tremor, anxiety, headache, sweating, palpitations, fast heartbeat, nausea, dizziness, high blood pressure, and pallor. Serious problems can include chest pain, dangerous arrhythmias, severe hypertension, stroke-like symptoms, tissue damage from extravasation, or worsening heart strain in susceptible patients.

Important information

Adrenaline is time-critical in anaphylaxis and cardiac arrest, but route and dilution must match the indication. Extra caution is needed in heart disease, severe hypertension, hyperthyroidism, diabetes, pregnancy, older age, and interactions with beta-blockers, tricyclic antidepressants, MAO inhibitors, or other sympathomimetics. Emergency care should continue even if symptoms initially improve.