Acetylcysteine 400mg/2mL Injection

Product Introduction

Acetylcysteine 400mg/2mL Injection is an injectable acetylcysteine preparation used in hospital or emergency-care settings. This is not a routine cough medicine or general antioxidant supplement.

How to use

Acetylcysteine 400mg/2mL Injection is administered by a doctor or nurse as an intravenous infusion after dilution according to the clinical protocol. The dose is weight-based and time-sensitive in paracetamol overdose. Vital signs, infusion tolerance, liver tests, coagulation markers, kidney function, and paracetamol levels may be monitored depending on the case. Do not self-administer or use an opened vial for later intravenous use.

How it works

Acetylcysteine provides cysteine for glutathione synthesis. Glutathione helps neutralize the toxic paracetamol metabolite NAPQI and supports liver-cell recovery. When given early after overdose, acetylcysteine can markedly reduce the risk of severe liver injury; it may still be useful later in selected patients under specialist guidance.

Common side effects

Possible effects include nausea, vomiting, flushing, itching, rash, fever, wheezing, chest tightness, dizziness, low blood pressure, or infusion-site discomfort. Serious reactions can include anaphylactoid reactions, bronchospasm, severe hypotension, breathing difficulty, and fluid overload, especially in small patients or people requiring fluid restriction. Infusion should be stopped and urgent treatment started if a serious reaction occurs.

Important information

This medicine is for supervised emergency or inpatient use. Dose and dilution must be checked against body weight and poisoning protocol. Extra caution is needed in asthma, previous acetylcysteine reaction, fluid restriction, low body weight, pregnancy, severe vomiting, liver injury, kidney disease, or uncertain overdose timing. Do not delay urgent medical care after suspected paracetamol overdose while waiting for symptoms; early treatment is most protective.