Fosaprepitant Dimeglumine 150mg Injection$35.00
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Fosaprepitant Dimeglumine 150mg Injection
SKU GME1414Digestive Care
Product Introduction
Fosaprepitant Dimeglumine 150mg is an intravenous antiemetic used with other medicines to prevent nausea and vomiting caused by cancer chemotherapy, including delayed symptoms after the treatment day.
How to use
After reconstitution and dilution, it is infused into a vein before chemotherapy. It is used with a serotonin-receptor antagonist and usually dexamethasone; the steroid dose is adjusted for the interaction.
How it works
Fosaprepitant is converted to aprepitant, which blocks substance P at neurokinin-1 receptors involved in the vomiting reflex.
Side effects
Headache, hiccups, fatigue and infusion-site irritation can occur. Severe hypersensitivity and significant infusion-site reactions are important risks.
Important information
Warfarin and several CYP3A-interacting medicines need review. Hormonal contraception may be less reliable during treatment and for a period afterwards, so additional non-hormonal protection is needed.
Uses
- Prevention of acute and delayed chemotherapy-induced nausea and vomiting.
Benefits
Adds protection against delayed vomiting when used as part of a multi-drug antiemetic regimen.
Is it intended to stop vomiting that has already started?
Its main role is prevention around chemotherapy. Breakthrough vomiting may need an additional rescue antiemetic.
Why are several anti-sickness medicines combined?
They block different vomiting pathways and provide broader protection than one medicine alone.
Is an oral aprepitant capsule automatically needed after this infusion?
Not in every regimen. A single-dose fosaprepitant schedule can replace a multi-day oral aprepitant schedule.
Why might my dexamethasone dose be lower?
Aprepitant increases dexamethasone exposure, so antiemetic regimens account for that interaction.
Antiemetic: a medicine that prevents or reduces vomiting. NK1 receptor: a receptor activated by substance P. Delayed nausea: nausea occurring after the first 24 hours of chemotherapy.; AR: Fosaprepitant Dimeglumine 150mg حقن; FR: Fosaprepitant Dimeglumine 150mg injection; PT: Fosaprepitant Dimeglumine 150mg injeção; ES: Fosaprepitant Dimeglumine 150mg inyección; RU: Fosaprepitant Dimeglumine 150mg инъекция; ID: Fosaprepitant Dimeglumine 150mg suntikan; VI: Fosaprepitant Dimeglumine 150mg thuốc tiêm; MS: Fosaprepitant Dimeglumine 150mg suntikan; TL: Fosaprepitant Dimeglumine 150mg iniksyon; ZH-SG: Fosaprepitant Dimeglumine 150mg 注射剂