Trastuzumab Emtansine 100mg Injection$476.00
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Trastuzumab Emtansine 100mg Injection
SKU GME1480Oncology Care
Product Introduction
Trastuzumab Emtansine 100mg is a HER2-directed antibody-drug conjugate used in selected HER2-positive breast cancers. It combines a targeting antibody with the microtubule-inhibiting payload DM1.
How to use
After reconstitution and dilution, it is administered by intravenous infusion, usually every 3 weeks. The first infusion is generally given over 90 minutes, with later infusions over 30 minutes if tolerated.
How it works
The trastuzumab component binds HER2 and delivers DM1 into the tumour cell. DM1 disrupts microtubules and blocks cell division.
Side effects
Fatigue, nausea, low platelets, raised liver enzymes and peripheral neuropathy can occur. Serious liver injury, heart dysfunction and lung inflammation are important risks.
Important information
Platelets, liver tests and heart function are monitored. It is not interchangeable with unconjugated trastuzumab or trastuzumab deruxtecan. Pregnancy must be avoided during treatment.
Uses
- Selected HER2-positive metastatic breast cancer and appropriate residual-disease adjuvant settings.
Benefits
Delivers a cytotoxic payload to HER2-expressing cells and can improve control of eligible breast cancer.
Is the vial dose the same as ordinary trastuzumab?
No. The emtansine conjugate has its own weight-based dose and must not be substituted by matching milligrams.
Why might platelets delay a treatment cycle?
Low platelets increase bleeding risk and may need time to recover before another infusion.
Why is HER2 testing required?
The antibody needs the HER2 target to deliver its payload effectively, so tumour testing is part of treatment selection.
Why can numb fingers or toes affect the dose plan?
DM1 can cause peripheral neuropathy, and worsening symptoms may require a treatment interruption or dose reduction.
Antibody-drug conjugate: an antibody linked to a cytotoxic payload. DM1: the microtubule-inhibiting component of emtansine. Thrombocytopenia: a low platelet count.; AR: Trastuzumab Emtansine 100mg حقن; FR: Trastuzumab Emtansine 100mg injection; PT: Trastuzumab Emtansine 100mg injeção; ES: Trastuzumab Emtansine 100mg inyección; RU: Trastuzumab Emtansine 100mg инъекция; ID: Trastuzumab Emtansine 100mg suntikan; VI: Trastuzumab Emtansine 100mg thuốc tiêm; MS: Trastuzumab Emtansine 100mg suntikan; TL: Trastuzumab Emtansine 100mg iniksyon; ZH-SG: Trastuzumab Emtansine 100mg 注射剂