Trabectedin 1mg Infusion$320.00
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Trabectedin 1mg Infusion
SKU GME1476Oncology Care
Product Introduction
Trabectedin 1mg is a DNA-binding chemotherapy used in selected advanced soft-tissue sarcomas, particularly after previous treatment. It is delivered as a prolonged intravenous infusion.
How to use
The reconstituted and diluted dose is generally infused over 24 hours through a central venous line in a repeating treatment cycle. Dexamethasone premedication is given before treatment to reduce toxicity and nausea.
How it works
Trabectedin binds within the minor groove of DNA and disrupts transcription, DNA repair and cellular responses that support tumour survival.
Side effects
Nausea, fatigue, low blood counts and raised liver enzymes can occur. Rhabdomyolysis, severe liver injury and cardiac dysfunction are important serious risks.
Important information
Blood counts, liver tests and creatine phosphokinase are checked before treatment. Report marked muscle pain, weakness or dark urine promptly.
Uses
- Selected advanced or metastatic soft-tissue sarcomas after suitable prior therapy.
Benefits
Can slow progression of susceptible sarcomas and support continuing disease control.
Why is a central line usually used?
A 24-hour infusion and the risk of tissue injury make reliable central access preferable.
Why is a muscle-enzyme blood test needed?
A rise in creatine phosphokinase can indicate muscle injury before severe rhabdomyolysis develops.
Can treatment continue if liver enzymes have not recovered?
The next cycle may need to be delayed or adjusted because liver recovery is part of the dosing criteria.
What should I do if the infusion pump stops at home?
Contact the oncology infusion service promptly; do not change the pump rate or reconnect a damaged line yourself.
Soft-tissue sarcoma: cancer arising in tissues such as muscle or fat. CPK: a blood enzyme used to assess muscle injury. Rhabdomyolysis: breakdown of muscle tissue.; AR: Trabectedin 1mg تسريب وريدي; FR: Trabectedin 1mg perfusion; PT: Trabectedin 1mg infusão; ES: Trabectedin 1mg perfusión; RU: Trabectedin 1mg инфузия; ID: Trabectedin 1mg infus; VI: Trabectedin 1mg dịch truyền; MS: Trabectedin 1mg infusi; TL: Trabectedin 1mg pagbubuhos sa ugat; ZH-SG: Trabectedin 1mg 静脉输液