Temozolomide 20mg Capsules

Product Introduction

Temozolomide 20mg is an oral alkylating chemotherapy used for glioblastoma and selected other malignant gliomas. It may be given with radiotherapy and then in separate maintenance cycles.

How to use

Swallow the capsules whole on an empty stomach, consistently in relation to meals. Take the anti-sickness medicine at the planned time beforehand. Radiotherapy-phase dosing and 5-day maintenance cycles use different schedules.

How it works

Temozolomide forms an active methylating compound that damages tumour-cell DNA. It reaches the central nervous system after oral administration.

Side effects

Nausea, vomiting, constipation, fatigue and low blood counts can occur. Serious infection, liver injury and prolonged marrow suppression are important risks.

Important information

PJP prophylaxis is needed during the prolonged daily regimen with radiotherapy and may continue while lymphocytes remain low. Do not open capsules or inhale their contents.