Sirolimus 0.1% w/w, 20g Cream$48.00
1–9 boxes
$48.00 each
10–24 boxes
8% off
25+ boxes
10% off
Sirolimus 0.1% w/w, 20g Cream
SKU GME1486Skin Care
Product Introduction
Sirolimus 0.1% w/w, 20g is a topical mTOR inhibitor used for facial angiofibromas associated with tuberous sclerosis complex. This skin preparation is not an oral transplant-rejection medicine.
How to use
Apply a thin layer to clean, dry affected skin using the dermatology treatment schedule. Keep it out of the eyes, mouth and open wounds. Wash hands afterwards and avoid covering the area with an occlusive dressing.
How it works
Sirolimus inhibits mTOR signalling involved in abnormal cell growth and blood-vessel formation, helping reduce the prominence of angiofibromas.
Side effects
Local dryness, irritation, itching and acne-like reactions can occur. Marked inflammation, skin infection or an allergic reaction needs assessment.
Important information
Use sun protection on treated skin. The 0.1% cream and other sirolimus gels differ in formulation and should not be assigned the same application schedule without considering the preparation.
Uses
- Facial angiofibromas associated with tuberous sclerosis complex.
Benefits
Can reduce the redness, thickness and visibility of treated facial lesions.
Does the cream treat all features of tuberous sclerosis?
No. Its role is local treatment of the specified skin lesions, not treatment of internal-organ involvement.
Can improvement require continuing treatment?
Yes. Lesions may become more noticeable again after treatment stops, so response and ongoing application are reviewed over time.
Can exfoliating acids be applied on the same area?
They can add irritation. A simple, non-irritating skin-care routine is preferable while tolerance is established.
Is the cream a substitute for sirolimus tablets after a transplant?
No. Topical and systemic formulations have entirely different treatment roles.
mTOR: a signalling pathway regulating cell growth. Angiofibroma: a benign lesion containing blood vessels and fibrous tissue. Tuberous sclerosis complex: an inherited condition affecting several organs.; AR: Sirolimus 0.1% w/w, 20g كريم; FR: Sirolimus 0.1% w/w, 20g crème; PT: Sirolimus 0.1% w/w, 20g creme; ES: Sirolimus 0.1% w/w, 20g crema; RU: Sirolimus 0.1% w/w, 20g крем; ID: Sirolimus 0.1% w/w, 20g krim; VI: Sirolimus 0.1% w/w, 20g kem bôi da; MS: Sirolimus 0.1% w/w, 20g krim; TL: Sirolimus 0.1% w/w, 20g krema; ZH-SG: Sirolimus 0.1% w/w, 20g 乳膏