Rucaparib 200mg Tablets$516.00
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Rucaparib 200mg Tablets
SKU GME1466Oncology Care
Product Introduction
Rucaparib 200mg is a PARP inhibitor used in selected ovarian and prostate-cancer treatment settings. Eligibility depends on the disease setting, prior response and relevant DNA-repair or BRCA findings.
How to use
Swallow the tablets whole at the scheduled twice-daily times, with or without food. Do not repeat a vomited dose or double the next dose after a missed one.
How it works
Rucaparib inhibits PARP enzymes involved in DNA repair. Cancer cells with impaired alternative repair pathways are particularly vulnerable to the resulting DNA damage.
Side effects
Nausea, fatigue, anaemia, taste changes and raised liver enzymes can occur. Persistent marrow disorders and severe photosensitivity are important risks.
Important information
Blood counts and liver tests are monitored. Use sun protection and avoid excessive ultraviolet exposure. Pregnancy must be avoided during treatment.
Uses
- Selected biomarker- and treatment-eligible ovarian or prostate-cancer settings.
Benefits
Can prolong disease control in cancers with treatment characteristics that support PARP inhibition.
Why might BRCA testing be needed?
A BRCA alteration or other defined disease criteria can determine whether this PARP-inhibitor regimen is appropriate.
Can treatment make sunlight more irritating?
Yes. Photosensitivity can cause easier sunburn, so protective clothing and sunscreen are useful.
Does a raised creatinine always mean kidney damage?
Rucaparib can affect creatinine transport as well as kidney function; the result needs clinical interpretation rather than an automatic conclusion.
Why is persistent anaemia investigated?
Most anaemia is treatment related, but prolonged or unexplained low counts can require marrow assessment.
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