Rivaroxaban 10mg Tablets

Product Introduction

Rivaroxaban 10mg is an oral anticoagulant used to prevent deep-vein thrombosis and pulmonary embolism after hip or knee replacement, and to reduce recurrence after an initial clot-treatment course.

How to use

The 10mg prevention dose is commonly taken once daily, with or without food. After surgery, the first dose is timed after bleeding has been controlled. The duration depends on the specific prevention setting and is not the same for every operation or patient.

How it works

Rivaroxaban directly inhibits activated factor X, or factor Xa. This reduces thrombin generation and the formation of fibrin clots without acting as a platelet inhibitor like aspirin.

Side effects

Bruising, nosebleeds, gum bleeding and anaemia can occur. Bleeding that will not stop, black stools, blood in urine, vomiting blood, a severe headache after a fall or sudden weakness needs urgent assessment.

Important information

Do not use during active significant bleeding or liver disease that impairs clotting. Kidney function affects the choice of dose and regimen. Strong CYP3A4/P-glycoprotein inhibitors or inducers can alter rivaroxaban levels. Tell the surgical or dental team before a procedure, particularly a spinal or epidural procedure. NSAIDs, antiplatelets and other anticoagulants increase bleeding risk. The 10mg prevention tablet does not replace the initial higher-dose regimen for a newly diagnosed DVT or pulmonary embolism.