Relugolix 120mg Tablets

Product Introduction

Relugolix 120mg is an oral hormone therapy for advanced prostate cancer. It lowers testosterone to help control cancers that depend on male hormones for growth.

How to use

Take the tablets once daily, with or without food, swallowing them whole. Treatment starts with a larger loading dose before changing to the 120mg daily maintenance dose. A break longer than seven days requires reassessment of the loading schedule rather than simply restarting the old routine.

How it works

Relugolix blocks gonadotropin-releasing hormone receptors in the pituitary gland. This quickly reduces LH and FSH signalling and lowers testosterone without the initial testosterone surge associated with GnRH agonists.

Side effects

Hot flushes, tiredness, muscle or joint pain, constipation or diarrhoea can occur. Blood glucose, blood fats and liver tests may change. Fainting, palpitations or chest pain need urgent assessment.

Important information

Heart-rhythm history, low potassium or magnesium and medicines that prolong the QT interval are relevant before treatment. Oral P-glycoprotein inhibitors can substantially raise relugolix exposure. Long-term testosterone suppression can affect bone density, sexual function and metabolic health.