Regorafenib 40mg Tablets

Product Introduction

Regorafenib 40mg is a multi-kinase inhibitor used in selected previously treated colorectal cancers, gastrointestinal stromal tumours and hepatocellular cancers. Its place in treatment depends on the cancer type and earlier therapy.

How to use

Swallow the tablets after a low-fat meal at a consistent time. A common cycle is 21 treatment days followed by 7 days off. Avoid grapefruit and strong enzyme-inducing medicines.

How it works

Regorafenib inhibits several kinases involved in tumour-cell growth, blood-vessel formation and the tumour environment.

Side effects

Hand-foot skin reactions, fatigue, diarrhoea, mouth soreness and high blood pressure can occur. Serious liver injury, bleeding and gastrointestinal perforation are important risks.

Important information

Liver tests and blood pressure are followed closely, particularly early in treatment. Report jaundice, severe abdominal pain or non-healing wounds. Planned surgery can require an interruption.