Rasburicase 1.5mg Injection$90.00
1–9 boxes
$90.00 each
10–24 boxes
8% off
25+ boxes
10% off
Rasburicase 1.5mg Injection
SKU GME1464Blood Care
Product Introduction
Rasburicase 1.5mg is a urate-oxidase enzyme used to control high uric acid around cancer treatment in people at risk of tumour lysis syndrome. It acts on uric acid already present in the bloodstream.
How to use
The reconstituted and diluted medicine is infused into a vein, usually over 30 minutes, as a short treatment course. Uric-acid results and the tumour-lysis plan determine further doses.
How it works
Rasburicase converts uric acid into allantoin, a more soluble substance that can be removed through the kidneys.
Side effects
Nausea, fever, headache and rash can occur. Haemolysis, methaemoglobinaemia and severe hypersensitivity are important serious risks.
Important information
It must not be used in G6PD deficiency. Uric-acid blood samples require special chilled handling because the enzyme can continue breaking down uric acid in the sample.
Uses
- Prevention and treatment of tumour-lysis-associated hyperuricaemia in appropriate cancer-treatment settings.
Benefits
Rapidly lowers circulating uric acid and helps reduce uric-acid-related kidney complications.
How is it different from allopurinol?
Allopurinol reduces formation of new uric acid; rasburicase breaks down uric acid already present.
Why is G6PD status important?
G6PD deficiency increases the risk of severe red-cell destruction and abnormal haemoglobin oxidation.
Why might the laboratory need a sample kept on ice?
Continued enzyme activity after collection can produce a falsely low uric-acid result unless the sample is handled correctly.
Does it correct all parts of tumour lysis syndrome?
No. Potassium, phosphate, calcium, fluid balance and kidney function need separate monitoring and management.
Uric acid: a breakdown product of purines. Allantoin: a more soluble uric-acid breakdown product. Tumour lysis syndrome: metabolic changes caused by rapid tumour-cell breakdown.; AR: Rasburicase 1.5mg حقن; FR: Rasburicase 1.5mg injection; PT: Rasburicase 1.5mg injeção; ES: Rasburicase 1.5mg inyección; RU: Rasburicase 1.5mg инъекция; ID: Rasburicase 1.5mg suntikan; VI: Rasburicase 1.5mg thuốc tiêm; MS: Rasburicase 1.5mg suntikan; TL: Rasburicase 1.5mg iniksyon; ZH-SG: Rasburicase 1.5mg 注射剂