Plerixafor 24mg/1.2mL Injection$560.00
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$560.00 each
10–24 boxes
8% off
25+ boxes
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Plerixafor 24mg/1.2mL Injection
SKU GME1332Blood Care
Product Introduction
Plerixafor 24mg is a stem-cell mobilisation medicine used with G-CSF before collection of a patient’s own blood stem cells for transplantation in selected myeloma or lymphoma settings.
How to use
The clinical team gives a subcutaneous injection timed before apheresis, commonly about 11 hours before collection. Body weight and kidney function determine the regimen. G-CSF forms part of the mobilisation course.
How it works
Plerixafor blocks CXCR4 signalling, disrupting retention of stem cells in the marrow and allowing more to enter circulating blood.
Side effects
Diarrhoea, nausea, injection-site reactions, headache and dizziness can occur. Severe abdominal or left shoulder pain, allergic symptoms or fainting needs prompt assessment.
Important information
Blood counts and circulating CD34-positive cells guide collection. Splenic enlargement or rupture is a rare concern. Mobilisation in leukaemia can release malignant cells and is not its usual role.
Uses
- Mobilisation of haematopoietic stem cells with G-CSF for autologous transplantation in selected lymphoma or multiple myeloma patients.
Benefits
Increasing circulating stem cells can improve the chance of collecting a sufficient transplant graft.
Is it the transplant itself?
No. It helps move stem cells into the blood so that they can be collected and stored for a later transplant.
Why is the injection timed so closely to collection?
The rise in circulating stem cells follows a predictable time course, which the apheresis schedule uses.
Can it replace G-CSF?
It is generally used together with G-CSF rather than as an assumed substitute.
What is measured before collection?
Circulating CD34-positive cells help estimate whether enough stem cells are available for apheresis.
Apheresis: separation and collection of selected blood components. CD34: a marker used to identify blood stem cells. Autologous transplant: transplantation using the patient’s own cells.; AR: Plerixafor 24mg حقن; FR: Plerixafor 24mg injection; PT: Plerixafor 24mg injeção; ES: Plerixafor 24mg inyección; RU: Plerixafor 24mg инъекция; ID: Plerixafor 24mg suntikan; VI: Plerixafor 24mg thuốc tiêm; MS: Plerixafor 24mg suntikan; TL: Plerixafor 24mg iniksyon; ZH-SG: Plerixafor 24mg 注射剂