Pemetrexed 100mg Injection$51.00
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$51.00 each
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Pemetrexed 100mg Injection
SKU GME1460Oncology Care
Product Introduction
Pemetrexed 100mg is an antifolate chemotherapy used in non-squamous non-small-cell lung cancer and malignant pleural mesothelioma. It may be used with other anticancer medicines or as maintenance treatment in suitable settings.
How to use
The prepared dose is infused into a vein, usually over about 10 minutes in a 21-day cycle. Daily folic acid begins before treatment, and vitamin B12 injections and corticosteroid premedication are incorporated into the regimen.
How it works
Pemetrexed inhibits several folate-dependent enzymes needed to make DNA and RNA, limiting the growth of dividing tumour cells.
Side effects
Fatigue, low blood counts, nausea, reduced appetite, rash and mouth soreness can occur. Serious infection, kidney injury and severe skin reactions are important risks.
Important information
Kidney function is critical to clearance. NSAIDs such as ibuprofen can affect exposure around treatment, particularly when kidney function is reduced. Vitamin supplementation reduces toxicity.
Uses
- Non-squamous non-small-cell lung cancer and malignant pleural mesothelioma.
Benefits
Can improve disease control in appropriate lung-cancer or mesothelioma regimens.
Why is folic acid started before the first infusion?
It reduces severe blood and gastrointestinal toxicity without replacing the anticancer medicine.
Can oral vitamin B12 replace the scheduled injection?
No. The established pemetrexed regimen uses intramuscular B12 supplementation.
Why is dexamethasone used around treatment?
It reduces the risk and severity of pemetrexed-associated skin rash.
Is pemetrexed used for every lung-cancer subtype?
No. Its established role is in non-squamous disease rather than squamous non-small-cell lung cancer.
Antifolate: a medicine blocking folate-dependent processes. Non-squamous: a lung-cancer grouping excluding squamous histology. Mesothelioma: a cancer of tissue lining body cavities.; AR: Pemetrexed 100mg حقن; FR: Pemetrexed 100mg injection; PT: Pemetrexed 100mg injeção; ES: Pemetrexed 100mg inyección; RU: Pemetrexed 100mg инъекция; ID: Pemetrexed 100mg suntikan; VI: Pemetrexed 100mg thuốc tiêm; MS: Pemetrexed 100mg suntikan; TL: Pemetrexed 100mg iniksyon; ZH-SG: Pemetrexed 100mg 注射剂