Pegfilgrastim 6mg/0.6mL Injection

Product Introduction

Pegfilgrastim 6mg/0.6mL is a long-acting granulocyte-colony stimulating factor used to reduce chemotherapy-associated febrile neutropenia. It supports white-cell recovery and is not an anticancer medicine itself.

How to use

It is injected under the skin once per chemotherapy cycle when appropriate, at least 24 hours after cytotoxic chemotherapy. It is not given within 14 days before the next cytotoxic course unless a specific validated treatment plan applies.

How it works

Pegfilgrastim stimulates marrow production and release of neutrophils. Pegylation prolongs its activity compared with short-acting filgrastim.

Side effects

Bone pain and pain in the limbs are common. Severe allergy, splenic rupture, acute respiratory distress and aortitis are rare serious risks.

Important information

Left upper-abdominal or shoulder-tip pain, sudden breathlessness or persistent unexplained fever needs urgent assessment. Sickle-cell disease requires particular caution.