Pazopanib Hydrochloride 400mg Tablets$230.00
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$230.00 each
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Pazopanib Hydrochloride 400mg Tablets
SKU GME1312Oncology Care
Product Introduction
Pazopanib Hydrochloride 400mg is a targeted anticancer medicine for advanced renal-cell cancer and selected previously treated soft-tissue sarcomas. It limits signalling that supports tumour growth and blood supply.
How to use
Take on an empty stomach, at least 1 hour before or 2 hours after food. Swallow tablets whole. Do not crush. Avoid grapefruit, and do not double a missed dose.
How it works
Pazopanib inhibits several receptor tyrosine kinases, including VEGF receptors, reducing angiogenesis and growth signalling.
Side effects
Diarrhoea, fatigue, reduced appetite, nausea, high blood pressure and hair-colour changes can occur. Liver injury, significant bleeding or severe abdominal pain needs urgent assessment.
Important information
Liver function and blood pressure require monitoring. Acid-suppressing medicines can reduce absorption. Strong CYP3A modifiers, recent surgery and heart-rhythm problems are important.
Uses
- Advanced renal-cell carcinoma and selected advanced soft-tissue sarcoma after prior treatment.
Benefits
In an appropriate tumour setting, targeted kinase inhibition can slow progression and help maintain disease control.
Why should it not be taken with a meal?
Food can substantially increase drug exposure and toxicity. A consistent fasting interval is essential.
Can omeprazole affect treatment?
Raising stomach pH can reduce pazopanib absorption. The acid-suppression plan may need changing.
Is a change in hair colour treatment failure?
Hair depigmentation is a recognised drug effect and does not by itself show whether the tumour is responding.
Why may treatment pause around an operation?
Inhibition of blood-vessel growth can impair wound healing. Surgery requires a planned interruption and restart.
Angiogenesis: formation of new blood vessels. Tyrosine kinase: an enzyme involved in cell signalling. Soft-tissue sarcoma: cancer arising from connective or supporting tissues.; AR: Pazopanib Hydrochloride 400mg أقراص; FR: Pazopanib Hydrochloride 400mg comprimés; PT: Pazopanib Hydrochloride 400mg comprimidos; ES: Pazopanib Hydrochloride 400mg comprimidos; RU: Pazopanib Hydrochloride 400mg таблетки; ID: Pazopanib Hydrochloride 400mg tablet; VI: Pazopanib Hydrochloride 400mg viên nén; MS: Pazopanib Hydrochloride 400mg tablet; TL: Pazopanib Hydrochloride 400mg mga tableta; ZH-SG: Pazopanib Hydrochloride 400mg 片剂