Olaparib 100mg Tablets$168.00
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$168.00 each
10–24 boxes
8% off
25+ boxes
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Olaparib 100mg Tablets
SKU GME1456Oncology Care
Product Introduction
Olaparib 100mg is a PARP inhibitor used in selected ovarian, breast, pancreatic and prostate cancers. Eligibility depends on the cancer setting and relevant genetic or DNA-repair findings.
How to use
Swallow the tablets whole at the scheduled times, with or without food. Do not crush or dissolve them. Avoid grapefruit and Seville oranges. Skip a missed dose rather than doubling the next one.
How it works
Olaparib blocks PARP-mediated DNA repair and traps PARP on damaged DNA, making susceptible DNA-repair-deficient cancer cells less able to survive.
Side effects
Anaemia, nausea, fatigue, vomiting and reduced appetite can occur. Persistent marrow disorders and lung inflammation are uncommon but important serious risks.
Important information
Blood counts and kidney function guide treatment. Strong CYP3A inhibitors or inducers can substantially alter exposure. Pregnancy prevention remains necessary during treatment.
Uses
- Selected biomarker-eligible ovarian, breast, pancreatic and prostate cancer settings.
Benefits
Can delay progression or maintain a response in cancers with the appropriate treatment characteristics.
Why is genetic or tumour testing relevant?
BRCA and other DNA-repair findings can help identify cancers likely to benefit and determine eligibility for a particular regimen.
Are older olaparib capsules equivalent to tablets?
No. They have different bioavailability and are not interchanged by matching the milligram dose.
Why are blood counts checked even after earlier tests were normal?
Anaemia or other marrow effects can develop during continuing treatment and may require an interruption.
Can St John’s wort be taken alongside it?
No. It can lower olaparib exposure through enzyme induction and reduce treatment effectiveness.
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