Nilotinib 200mg Capsules

Nilotinib 200mg is a BCR-ABL tyrosine-kinase inhibitor used for Philadelphia chromosome-positive chronic myeloid leukaemia. Molecular response and previous treatment help determine the regimen.
Take the scheduled doses approximately 12 hours apart. Have no food for at least 2 hours before and 1 hour after each dose. Swallow the capsules with water and avoid grapefruit.
Nilotinib inhibits BCR-ABL kinase activity, reducing the abnormal growth signal responsible for Ph-positive leukaemia-cell proliferation.
Rash, itching, nausea, headache and low blood counts may occur. QT prolongation, arterial vascular events and pancreatitis are important risks.
ECG, potassium, magnesium, glucose and lipid monitoring may be needed. Low electrolytes and medicines that prolong QT can increase arrhythmia risk.
Can reduce the molecular leukaemia burden and help maintain long-term disease control.
Food can markedly increase nilotinib exposure and contribute to cardiac toxicity.
It detects changes in cardiac repolarisation that may not cause early symptoms.
No. Treatment-free remission is considered only with defined eligibility and intensive molecular follow-up.
Skip it and take the next scheduled dose at the usual time. Do not take two doses together.
Philadelphia chromosome: a chromosome change producing BCR-ABL. QT interval: an ECG measure of cardiac electrical recovery. Molecular remission: very low disease levels measured by genetic testing.; AR: Nilotinib 200mg كبسولات; FR: Nilotinib 200mg gélules; PT: Nilotinib 200mg cápsulas; ES: Nilotinib 200mg cápsulas; RU: Nilotinib 200mg капсулы; ID: Nilotinib 200mg kapsul; VI: Nilotinib 200mg viên nang; MS: Nilotinib 200mg kapsul; TL: Nilotinib 200mg mga kapsula; ZH-SG: Nilotinib 200mg 胶囊
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Nilotinib 200mg Capsules