Leuprolide Acetate 45mg Depot Injection$460.00
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Leuprolide Acetate 45mg Depot Injection
SKU GME1438Oncology Care
Product Introduction
Leuprolide Acetate 45mg is a long-acting gonadotropin-releasing-hormone agonist used in advanced prostate cancer. The 45mg depot provides sustained hormone suppression over a six-month treatment interval.
How to use
The two-syringe depot system is mixed and administered under the skin by a trained professional. This six-month formulation is not given into a vein or substituted using the schedule of a monthly depot.
How it works
After an initial stimulation phase, continuous GnRH-receptor activation suppresses pituitary LH release and lowers testosterone production.
Side effects
Hot flushes, injection-site discomfort, fatigue, reduced sexual function and weight changes can occur. Bone loss and changes in glucose or cardiovascular risk are important with prolonged treatment.
Important information
Testosterone can rise temporarily at the start. Existing spinal metastases or urinary obstruction require particular attention during this initial flare period.
Uses
- Hormone suppression in advanced prostate cancer.
Benefits
Maintains prolonged testosterone suppression to help control androgen-dependent cancer activity.
Why can symptoms briefly worsen after the first injection?
The initial testosterone rise can cause a tumour flare before suppression develops. An additional antiandrogen may be used during that period.
Can another leuprolide depot use the same injection interval?
No. Monthly, three-monthly and six-monthly formulations have different strengths and release characteristics.
Why are testosterone levels measured with PSA?
Testosterone testing confirms that the depot is maintaining the intended hormone suppression.
Why is bone health part of long-term follow-up?
Sustained testosterone reduction can reduce bone density and increase fracture risk.
Depot: a formulation that releases medicine over an extended period. GnRH agonist: a medicine that ultimately suppresses sex-hormone production. Tumour flare: temporary worsening associated with an initial hormone rise.; AR: Leuprolide Acetate 45mg حقن; FR: Leuprolide Acetate 45mg injection; PT: Leuprolide Acetate 45mg injeção; ES: Leuprolide Acetate 45mg inyección; RU: Leuprolide Acetate 45mg инъекция; ID: Leuprolide Acetate 45mg suntikan; VI: Leuprolide Acetate 45mg thuốc tiêm; MS: Leuprolide Acetate 45mg suntikan; TL: Leuprolide Acetate 45mg iniksyon; ZH-SG: Leuprolide Acetate 45mg 注射剂