Lapatinib 250mg Tablets$41.00
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Lapatinib 250mg Tablets
SKU GME1433Oncology Care
Product Introduction
Lapatinib 250mg is a targeted kinase inhibitor used with other medicines for selected HER2-positive advanced breast cancers. HER2 testing and previous treatment determine its place in the regimen.
How to use
Take the full daily tablet dose together, at least 1 hour before or 1 hour after a meal, keeping the same relationship to food each day. Capecitabine, when used alongside it, has different food instructions.
How it works
Lapatinib inhibits the intracellular kinase activity of HER2 and EGFR, blocking signals that promote tumour-cell growth.
Side effects
Diarrhoea, rash, nausea and fatigue can occur. Liver injury, reduced heart pumping function and lung inflammation are important risks.
Important information
Liver tests and heart-function assessment are included in follow-up. Avoid grapefruit and strong CYP3A interactions. Persistent diarrhoea needs early treatment to prevent dehydration.
Uses
- Selected HER2-positive advanced or metastatic breast-cancer combination regimens.
Benefits
Can improve disease control when combined with a suitable chemotherapy or endocrine medicine.
Why are its food instructions different from capecitabine?
Food affects the absorption of the two medicines differently, so they are not automatically taken together at the same mealtime.
Is HER2 testing still needed if I have already had other treatment?
Yes. Demonstrating HER2-positive disease is important when selecting a HER2-directed regimen.
Why is liver monitoring continued after early doses are tolerated?
Liver injury can appear days or months after treatment begins.
Can I divide the daily tablets into several separate doses?
The daily dose is normally taken together; splitting it changes the planned administration pattern.
HER2: a growth-signalling receptor overexpressed in some breast cancers. EGFR: epidermal growth factor receptor. Endocrine therapy: treatment acting on hormone-dependent cancer growth.; AR: Lapatinib 250mg أقراص; FR: Lapatinib 250mg comprimés; PT: Lapatinib 250mg comprimidos; ES: Lapatinib 250mg comprimidos; RU: Lapatinib 250mg таблетки; ID: Lapatinib 250mg tablet; VI: Lapatinib 250mg viên nén; MS: Lapatinib 250mg tablet; TL: Lapatinib 250mg mga tableta; ZH-SG: Lapatinib 250mg 片剂