Itraconazole 65mg Capsules$63.00
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Itraconazole 65mg Capsules
SKU GME619Product Introduction
Itraconazole 65mg is an oral itraconazole formulation used for selected susceptible fungal infections. Enhanced-bioavailability preparations differ from conventional capsules in exposure and must not be substituted solely by comparing milligrams.
How to use
Take the capsule with or just after food and swallow it intact. The enhanced-bioavailability preparation is not interchangeable milligram-for-milligram with conventional capsules; keep the same formulation throughout the treatment course.
How it works
Inhibition of fungal lanosterol 14-alpha-demethylase reduces ergosterol synthesis, disrupting the fungal cell membrane.
Side effects
Nausea, abdominal pain, diarrhoea, headache and abnormal liver tests can occur.
Important information
Tell your doctor about heart failure, liver disease and every medicine you take. Itraconazole can worsen heart pumping function and has major CYP3A4 interactions.
Uses
- Susceptible fungal skin, nail or systemic infections as appropriate to the formulation
Benefits
Treats the fungal cause rather than merely suppressing itching or inflammation.
Can this 65mg formulation be exchanged for conventional itraconazole capsules?
Not by matching milligrams alone. Release design and absorption differ, so changing formulation requires a new treatment plan rather than a tablet-for-capsule substitution.
Does every itraconazole formulation respond to acid-reducing medicines in the same way?
No. Conventional capsules and enhanced-bioavailability preparations can differ in their response to gastric acidity. Tell the prescriber about proton-pump inhibitors, H2 blockers and antacids rather than transferring instructions from a different formulation.
Can I take a statin without telling the prescriber?
Some statins, particularly simvastatin and lovastatin, have contraindicated interactions with itraconazole.
Which symptoms could indicate heart failure?
New breathlessness, ankle swelling or rapid weight gain needs prompt review.
Which liver symptoms should I report?
Dark urine, yellow eyes, persistent nausea or loss of appetite requires assessment.
Can a nail look abnormal after the fungus is treated?
Yes. Normal nail appearance depends on healthy nail growing out and may take months.
Can topical cream replace treatment for a systemic infection?
No. Local and systemic formulations have different indications.
Why should recurring ringworm be reassessed?
Diagnosis, resistance, adherence and reinfection can all affect response; repeating courses without review may miss the cause.
Ergosterol: a component of fungal cell membranes. CYP3A4: an enzyme involved in many drug interactions. Bioavailability: the fraction of a dose reaching the circulation., AR: Itraconazole كبسولات, FR: Itraconazole gélules, PT: Itraconazole cápsulas, ES: Itraconazole cápsulas, RU: Itraconazole капсулы, ID: Itraconazole kapsul, VI: Itraconazole viên nang, MS: Itraconazole kapsul, TL: Itraconazole kapsula, ZH-SG: Itraconazole 胶囊