Itraconazole 100mg Capsules

Itraconazole 100mg is an oral triazole antifungal used for selected susceptible skin, nail and systemic fungal infections. The infection site and organism determine whether this formulation is appropriate.
Take conventional capsules immediately after a full meal and swallow them intact. Acid-suppressing medicines can reduce their absorption; oral solution and enhanced-bioavailability products are not interchangeable with conventional capsules.
Inhibition of fungal lanosterol 14-alpha-demethylase reduces ergosterol synthesis, disrupting the fungal cell membrane.
Nausea, abdominal pain, diarrhoea, headache and abnormal liver tests can occur.
Tell your doctor about heart failure, liver disease and every medicine you take. Itraconazole can worsen heart pumping function and has major CYP3A4 interactions.
Treats the fungal cause rather than merely suppressing itching or inflammation.
Do not substitute by arithmetic alone; absorption and approved regimens differ.
Yes. Proton-pump inhibitors, H2 blockers and antacids can reduce absorption of acid-dependent formulations.
Some statins, particularly simvastatin and lovastatin, have contraindicated interactions with itraconazole.
New breathlessness, ankle swelling or rapid weight gain needs prompt review.
Dark urine, yellow eyes, persistent nausea or loss of appetite requires assessment.
Yes. Normal nail appearance depends on healthy nail growing out and may take months.
No. Local and systemic formulations have different indications.
Diagnosis, resistance, adherence and reinfection can all affect response; repeating courses without review may miss the cause.
Ergosterol: a component of fungal cell membranes. CYP3A4: an enzyme involved in many drug interactions. Bioavailability: the fraction of a dose reaching the circulation., AR: Itraconazole كبسولات, FR: Itraconazole gélules, PT: Itraconazole cápsulas, ES: Itraconazole cápsulas, RU: Itraconazole капсулы, ID: Itraconazole kapsul, VI: Itraconazole viên nang, MS: Itraconazole kapsul, TL: Itraconazole kapsula, ZH-SG: Itraconazole 胶囊
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Itraconazole 100mg Capsules