Imatinib 400mg Tablets$70.00
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Imatinib 400mg Tablets
SKU GME1429Oncology Care
Product Introduction
Imatinib 400mg is a targeted tyrosine-kinase inhibitor used in BCR-ABL-positive chronic myeloid leukaemia, selected acute lymphoblastic leukaemia and susceptible gastrointestinal stromal tumours. Genetic and tumour testing help select the treatment.
How to use
Take with a meal and a large glass of water to reduce stomach and oesophageal irritation. Swallow the tablets whole without crushing or chewing. Take the scheduled dose at consistent times and avoid grapefruit.
How it works
Imatinib inhibits BCR-ABL, KIT and selected other tyrosine kinases that drive abnormal cell growth.
Side effects
Fluid retention, nausea, diarrhoea, muscle cramps, rash and low blood counts can occur. Significant liver injury and severe fluid retention are important risks.
Important information
Blood counts, liver function, kidney function and weight are monitored. Sudden weight gain, breathlessness or increasing swelling can indicate excess fluid.
Uses
- BCR-ABL-positive leukaemia and susceptible KIT-positive gastrointestinal stromal tumour treatment settings.
Benefits
Can produce sustained molecular responses in leukaemia or slow growth of susceptible stromal tumours.
Why is the medicine continued after blood counts improve?
A normal count does not prove that all disease-driving cells have gone. Molecular or tumour-response monitoring guides continuing treatment.
Can muscle cramps occur without the cancer worsening?
Yes. Cramps are a recognised treatment effect; their severity and other possible causes are assessed during follow-up.
Why might my weight be recorded regularly?
A rapid increase can reveal fluid retention before marked swelling or breathing symptoms appear.
Do all gastrointestinal stromal tumours respond?
No. Response depends on the tumour’s molecular characteristics, including the type of KIT or related mutation.
Tyrosine kinase: an enzyme involved in growth signalling. GIST: gastrointestinal stromal tumour. Molecular response: a change in disease measured by genetic testing.; AR: Imatinib 400mg أقراص; FR: Imatinib 400mg comprimés; PT: Imatinib 400mg comprimidos; ES: Imatinib 400mg comprimidos; RU: Imatinib 400mg таблетки; ID: Imatinib 400mg tablet; VI: Imatinib 400mg viên nén; MS: Imatinib 400mg tablet; TL: Imatinib 400mg mga tableta; ZH-SG: Imatinib 400mg 片剂