Hydroxyurea 500mg Capsules$40.00
1–9 boxes
$40.00 each
10–24 boxes
8% off
25+ boxes
10% off
Hydroxyurea 500mg Capsules
SKU GME1420Blood Care
Product Introduction
Hydroxyurea 500mg is an oral antimetabolite used in selected blood disorders, including sickle-cell disease and certain myeloproliferative conditions. It may also be used in specific cancer regimens.
How to use
Swallow the capsules whole with water at a consistent time, with or without food. Do not open them or handle spilled powder. Blood counts and kidney function determine the continuing dose.
How it works
Hydroxyurea inhibits ribonucleotide reductase and limits DNA synthesis. In sickle-cell disease it also increases fetal haemoglobin, reducing red-cell sickling.
Side effects
Low blood counts, nausea, mouth soreness and skin or nail changes can occur. Leg ulcers and serious infection are important problems during prolonged treatment.
Important information
Pregnancy must be avoided during treatment. Sun protection is important with long-term exposure. Reduced kidney function can require a lower dose.
Uses
- Sickle-cell disease, selected myeloproliferative disorders and specific cancer regimens.
Benefits
Can reduce painful sickle-cell complications or control excessive blood-cell production, depending on the treatment setting.
Is it a fast painkiller for a sickle-cell crisis?
No. Its benefit develops through sustained disease control; an acute painful crisis needs separate treatment.
Does a higher MCV always mean vitamin deficiency?
No. Hydroxyurea commonly increases red-cell size. The blood result is interpreted alongside the treatment and other findings.
Why can the dose be held even without symptoms?
A fall in neutrophils or platelets can be detected before an infection or bleeding develops.
Can a capsule be opened for swallowing difficulty?
Do not open this cytotoxic capsule. A suitable alternative formulation needs to be arranged rather than exposing the contents.
Fetal haemoglobin: a form of haemoglobin that reduces sickling. Myeloproliferative disorder: a condition with excess marrow-cell production. MCV: a measure of average red-cell size.; AR: Hydroxyurea 500mg كبسولات; FR: Hydroxyurea 500mg gélules; PT: Hydroxyurea 500mg cápsulas; ES: Hydroxyurea 500mg cápsulas; RU: Hydroxyurea 500mg капсулы; ID: Hydroxyurea 500mg kapsul; VI: Hydroxyurea 500mg viên nang; MS: Hydroxyurea 500mg kapsul; TL: Hydroxyurea 500mg mga kapsula; ZH-SG: Hydroxyurea 500mg 胶囊