Exemestane 25mg Tablets$90.00
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$90.00 each
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8% off
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Exemestane 25mg Tablets
SKU GME931Product Introduction
Exemestane 25mg is an aromatase inhibitor used for hormone-sensitive breast cancer in postmenopausal women. It is used in selected early breast cancer treatment plans after tamoxifen, and in advanced disease that has progressed after previous hormonal therapy.
How to use
Take the tablet once daily after a meal, at a consistent time. Treatment may continue for years in an adjuvant plan. If a dose is missed, take it when remembered unless the next dose is near; do not take two doses together.
How it works
Exemestane irreversibly inhibits aromatase, the enzyme that converts androgens to oestrogens. Lower oestrogen availability reduces stimulation of hormone-sensitive breast cancer cells.
Side effects
Hot flushes, sweating, joint pain, fatigue, headache, nausea or sleep disturbance can occur. Bone mineral density may fall, increasing fracture risk. Severe breathlessness, allergic swelling or significant liver-related symptoms need prompt assessment.
Important information
Bone density and vitamin D status are important during treatment. Oestrogen-containing medicines can oppose its action, while rifampicin, phenytoin and other strong enzyme inducers can lower exposure. Pregnancy and breastfeeding must be avoided during treatment.
Uses
- Adjuvant treatment of selected hormone-sensitive early breast cancers after tamoxifen
- advanced breast cancer after progression on previous hormonal treatment in postmenopausal women.
Benefits
Provides endocrine control of hormone-dependent cancer and can reduce recurrence risk in an appropriate adjuvant treatment sequence. The benefit depends on the tumour's hormone sensitivity and treatment setting.
Is exemestane chemotherapy?
It is endocrine therapy rather than conventional cytotoxic chemotherapy. It reduces an oestrogen signal that some breast cancers depend on for growth.
Why may exemestane be started after tamoxifen?
The medicines block oestrogen signalling in different ways. Switching after a defined tamoxifen period is one established adjuvant strategy for eligible postmenopausal patients.
Why do I need bone-health monitoring with exemestane?
Lower oestrogen levels can accelerate bone loss. Bone-density measurements and vitamin D assessment help identify when additional bone protection is needed.
Can I take hormone replacement therapy for hot flushes during treatment?
Oestrogen-containing therapy can interfere with the purpose of exemestane. Nonhormonal approaches may be considered for troublesome menopausal symptoms.
Does feeling well mean I can stop adjuvant exemestane?
No. Adjuvant treatment is intended to reduce future recurrence risk, not just treat symptoms. Feeling well does not show whether microscopic cancer cells remain.
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