Etoricoxib 60mg + Pregabalin 75mg PR Tablets

Product Introduction

Etoricoxib 60mg + Pregabalin 75mg tablet is used for selected mixed-pain conditions with both inflammatory and neuropathic features. It combines an anti-inflammatory medicine with treatment directed at abnormal nerve signalling.

How to use

Swallow the prolonged-release tablet whole with water; do not crush or chew it. Keep doses on the planned schedule. Avoid alcohol and do not drive if sleepy or dizzy. After regular pregabalin treatment, stopping requires gradual reduction to limit withdrawal symptoms; do not abruptly discontinue it when pain first improves.

How it works

Etoricoxib reduces inflammatory prostaglandins through COX-2 inhibition. Pregabalin reduces abnormal nerve excitability by binding alpha-2-delta calcium-channel subunits.

Side effects

Possible effects include sleepiness, dizziness, blurred vision, swelling, weight gain, dry mouth, constipation, indigestion, nausea, raised blood pressure, and headache. Serious warning signs include mood changes, severe drowsiness, breathing difficulty with sedatives/opioids, chest pain, black stools, or reduced urination.

Important information

Tell your doctor about kidney or heart disease, high blood pressure, depression, substance-use problems or swelling. Mention pregnancy, breastfeeding, alcohol, opioids, sedatives, blood thinners and other NSAIDs. Older adults may be more vulnerable to dizziness and sedation. Avoid NSAIDs from 20 weeks of pregnancy unless specifically necessary under obstetric supervision, and avoid them from 30 weeks because of fetal kidney and heart risks.