Dopamine Hydrochloride 40mg/mL, 5mL Injection$40.00
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$40.00 each
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Dopamine Hydrochloride 40mg/mL, 5mL Injection
SKU GME1404Critical Care
Product Introduction
Dopamine Hydrochloride injection is a catecholamine medicine used in monitored critical care to support circulation in selected patients with shock and severe low blood pressure. It can improve cardiac pumping and blood pressure while the underlying cause of circulatory failure is treated.
How to use
A critical-care professional dilutes the concentrate and gives it as a continuous intravenous infusion through an infusion pump, preferably into a large vein. It is not given as an undiluted IV bolus. Blood pressure, ECG, circulation, urine output and the infusion site are monitored while the rate is adjusted.
How it works
Dopamine stimulates beta-1 adrenergic receptors to increase the force of cardiac contraction. At higher infusion rates, alpha-adrenergic effects increase vascular tone. Its overall circulatory effect depends on the rate and the patient’s response.
Side effects
A fast or irregular heartbeat, palpitations, nausea, vomiting, headache and vasoconstriction can occur. Severe vasoconstriction or leakage outside the vein can cause tissue ischaemia or necrosis. Chest pain or cold, discoloured extremities needs immediate attention.
Important information
Low circulating volume, inadequate oxygenation and acidosis are corrected as part of shock treatment. Phaeochromocytoma is a contraindication. Previous rhythm problems, peripheral vascular disease and sulfite sensitivity are important. Alkaline solutions such as sodium bicarbonate are incompatible with dopamine.
Uses
- Haemodynamic support in selected patients with shock and severe hypotension when a dopamine infusion is appropriate.
Benefits
Can improve cardiac output and blood pressure during circulatory failure, supporting blood flow to vital organs while the cause of shock is treated.
How much dopamine is in each 5mL ampoule?
Each millilitre contains 40mg of dopamine hydrochloride. A full 5mL ampoule contains 200mg before dilution.
Why is the infusion rate changed during treatment?
Dopamine’s effects on heart contraction and blood-vessel tone vary with the infusion rate. The team adjusts delivery to blood pressure, circulation and tolerability rather than giving the whole ampoule as one dose.
What should I report at the infusion site?
Tell the nurse immediately about pain, burning, swelling, pale skin or coolness near the cannula. Dopamine leaking outside a vein can reduce local blood flow and injure tissue.
Is dopamine the same medicine as dobutamine?
No. Both can support cardiac pumping, but dopamine also has rate-dependent effects on vascular tone and blood pressure. They have different concentrations and infusion regimens and are not direct substitutes.
Can dopamine prevent kidney failure?
An increase in urine output does not establish kidney protection. Dopamine is used for haemodynamic support when appropriate; it is not routine treatment solely to prevent kidney injury.
Why is heart rhythm monitored during the infusion?
Dopamine can produce a fast or irregular heartbeat and increase the heart’s oxygen demand. Continuous rhythm monitoring helps the team detect these effects promptly.
Which medicines are especially important to mention before treatment?
Recent monoamine-oxidase inhibitors, linezolid, tricyclic antidepressants, other vasopressors and some anaesthetics can markedly change the blood-pressure or rhythm response. The critical-care team needs the recent medicine history, including treatments already stopped.
Why is the infusion reduced gradually when circulation improves?
Abrupt withdrawal can cause a sudden fall in blood pressure. The infusion is reduced in a controlled way while circulation and the need for fluids or other support are reassessed.
Catecholamine: a signalling substance that acts on cardiovascular receptors. Inotrope: a medicine that increases the strength of heart contraction. Vasopressor: a medicine that raises blood pressure by changing vascular tone. Extravasation: leakage of an infusion from a vein into surrounding tissue.; AR: Dopamine Hydrochloride 40mg/mL, 5mL حقن; FR: Dopamine Hydrochloride 40mg/mL, 5mL injection; PT: Dopamine Hydrochloride 40mg/mL, 5mL injeção; ES: Dopamine Hydrochloride 40mg/mL, 5mL inyección; RU: Dopamine Hydrochloride 40mg/mL, 5mL инъекция; ID: Dopamine Hydrochloride 40mg/mL, 5mL injeksi; VI: Dopamine Hydrochloride 40mg/mL, 5mL thuốc tiêm; MS: Dopamine Hydrochloride 40mg/mL, 5mL suntikan; TL: Dopamine Hydrochloride 40mg/mL, 5mL iniksyon; ZH-SG: Dopamine Hydrochloride 40mg/mL, 5mL 注射剂