Decitabine 50mg Injection$56.00
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8% off
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Decitabine 50mg Injection
SKU GME1392Oncology Care
Product Introduction
Decitabine 50mg is a hypomethylating chemotherapy used in myelodysplastic syndromes and selected acute myeloid leukaemia regimens. It is used to improve control of abnormal marrow-cell development over repeated treatment cycles.
How to use
The reconstituted medicine is infused into a vein on the treatment days of a defined cycle. Five-day and three-day schedules use different infusion durations; the oncology regimen determines which schedule applies.
How it works
Decitabine becomes incorporated into DNA and inhibits DNA methyltransferase. This can restore activity of genes involved in normal cell development and also damage abnormal cells.
Side effects
Low white cells, anaemia, low platelets, fever, nausea and fatigue can occur. Severe infection and bleeding are important risks during blood-count suppression.
Important information
Blood counts and kidney and liver function are followed during treatment. An early fall in counts can reflect treatment effects and does not by itself establish treatment failure.
Uses
- Myelodysplastic syndromes and selected acute myeloid leukaemia treatment regimens.
Benefits
Can improve marrow disease control and, in responding patients, reduce transfusion requirements.
Why can several cycles be needed before response is clear?
Changes in marrow-cell development take time. Response is assessed over planned cycles rather than from symptoms after the first infusion.
Is this the same as an oral decitabine combination?
No. Oral combinations include another ingredient that changes decitabine availability and cannot be substituted milligram for milligram.
Can I still need transfusions during treatment?
Yes. Transfusions may support low blood counts while the disease and treatment response are being assessed.
Why might a cycle be delayed?
Recovery from prolonged low counts, infection or organ toxicity may be needed before treatment resumes.
Hypomethylating agent: a medicine that reduces DNA methylation. Myelodysplastic syndrome: abnormal development of marrow blood cells. Transfusion dependence: a continuing need for donated blood components.; AR: Decitabine 50mg حقن; FR: Decitabine 50mg injection; PT: Decitabine 50mg injeção; ES: Decitabine 50mg inyección; RU: Decitabine 50mg инъекция; ID: Decitabine 50mg suntikan; VI: Decitabine 50mg thuốc tiêm; MS: Decitabine 50mg suntikan; TL: Decitabine 50mg iniksyon; ZH-SG: Decitabine 50mg 注射剂