Darbepoetin Alfa 25mcg/0.42mL Injection$34.00
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Darbepoetin Alfa 25mcg/0.42mL Injection
SKU GME1387Blood Care
Product Introduction
Darbepoetin Alfa 25mcg/0.42mL is a long-acting erythropoiesis-stimulating medicine used for anaemia associated with chronic kidney disease and selected chemotherapy-related anaemia. It increases red-cell production over time rather than providing immediate correction.
How to use
It is administered under the skin or into a vein according to the kidney or chemotherapy treatment schedule. Keep prefilled syringes refrigerated, do not shake them and allow the syringe to reach room temperature naturally before administration.
How it works
Darbepoetin activates erythropoietin receptors in the bone marrow, encouraging red-cell precursors to mature into circulating red blood cells.
Side effects
Raised blood pressure, headache and injection-site discomfort may occur. Blood clots and, rarely, severe allergic reactions or loss of red-cell production are serious risks.
Important information
Haemoglobin, blood pressure and iron availability are monitored. Increasing haemoglobin too rapidly or to an unnecessarily high level can raise cardiovascular risk.
Uses
- Anaemia due to chronic kidney disease and selected chemotherapy-associated anaemia.
Benefits
Can improve haemoglobin and reduce the need for red-cell transfusions when used in an appropriate anaemia treatment plan.
How soon will my haemoglobin rise?
A response usually develops over several weeks, so it does not replace a transfusion when anaemia requires urgent correction.
Why might iron treatment be needed as well?
Making additional red cells uses iron. Low available iron can limit the response even when the darbepoetin dose is adequate.
Does it treat every cause of anaemia?
No. Bleeding, vitamin deficiencies, haemolysis and other marrow problems need their own treatment.
Why is the dose sometimes reduced when the blood count improves?
The aim is sufficient anaemia control with the lowest effective exposure, rather than pushing haemoglobin back to a high normal value.
Erythropoiesis: production of red blood cells. Haemoglobin: the oxygen-carrying protein in red cells. Erythropoietin receptor: the receptor that signals red-cell production. Transfusion: administration of donated blood components.; AR: Darbepoetin Alfa 25mcg/0.42mL حقن; FR: Darbepoetin Alfa 25mcg/0.42mL injection; PT: Darbepoetin Alfa 25mcg/0.42mL injeção; ES: Darbepoetin Alfa 25mcg/0.42mL inyección; RU: Darbepoetin Alfa 25mcg/0.42mL инъекция; ID: Darbepoetin Alfa 25mcg/0.42mL suntikan; VI: Darbepoetin Alfa 25mcg/0.42mL thuốc tiêm; MS: Darbepoetin Alfa 25mcg/0.42mL suntikan; TL: Darbepoetin Alfa 25mcg/0.42mL iniksyon; ZH-SG: Darbepoetin Alfa 25mcg/0.42mL 注射剂