Crizotinib 250mg Capsules$96.00
1–9 boxes
$96.00 each
10–24 boxes
8% off
25+ boxes
10% off
Crizotinib 250mg Capsules
SKU GME1377Oncology Care
Product Introduction
Crizotinib 250mg is a targeted kinase inhibitor used for ALK- or ROS1-positive non-small-cell lung cancer and certain other ALK-positive tumours. Molecular testing identifies whether the cancer has one of these treatment targets.
How to use
Swallow capsules whole with water at the scheduled times, with or without food. Do not open, crush or chew. Avoid grapefruit. If fewer than 6 hours remain before the next dose, skip a missed dose.
How it works
Crizotinib inhibits ALK, ROS1 and MET signalling, reducing growth and survival of tumour cells driven by susceptible kinase abnormalities.
Side effects
Visual disturbances, nausea, diarrhoea, vomiting, oedema and fatigue can occur. Liver injury, pneumonitis, bradycardia and QT prolongation are important serious risks.
Important information
Liver tests, heart rate and relevant ECG or electrolyte checks guide treatment. CYP3A interactions can substantially alter exposure. New breathlessness, fainting or severe visual change needs prompt assessment.
Uses
- Selected ALK- or ROS1-positive non-small-cell lung cancer and other established ALK-positive tumour settings.
Benefits
In a molecularly matched cancer, kinase inhibition can shrink tumours and delay progression.
Why is a gene test needed before treatment?
It identifies a kinase abnormality that the medicine can target. Lung cancer alone does not establish a treatment match.
Are brief light trails a recognised effect?
Visual effects can occur, but a major change in vision, visual loss or a persistent symptom needs urgent assessment.
Can a beta blocker affect treatment safety?
Medicines that slow the heart can add to crizotinib-related bradycardia and may require adjustment.
Should I repeat a capsule if I vomit afterwards?
No. Take the next planned dose rather than replacing a vomited dose independently.
ALK and ROS1: genes that can produce cancer-driving fusion kinases. Bradycardia: a slow heart rate. Molecular selection: choosing treatment using tumour biomarkers.; AR: Crizotinib 250mg كبسولات; FR: Crizotinib 250mg gélules; PT: Crizotinib 250mg cápsulas; ES: Crizotinib 250mg cápsulas; RU: Crizotinib 250mg капсулы; ID: Crizotinib 250mg kapsul; VI: Crizotinib 250mg viên nang; MS: Crizotinib 250mg kapsul; TL: Crizotinib 250mg mga kapsula; ZH-SG: Crizotinib 250mg 胶囊