Capecitabine 1000mg Dispersible Tablets

Capecitabine 1000mg dispersible tablets are an oral fluoropyrimidine chemotherapy used for selected colorectal, breast and other gastrointestinal cancers.
Take within 30 minutes after a meal on the scheduled treatment days. For the dispersible presentation, place the required tablets in 100mL of drinking water, allow them to disperse and drink promptly. Rinse the container with a little water and drink the rinse to deliver the full dose. Avoid crushing or handling broken cytotoxic tablets.
Capecitabine is converted through several steps to fluorouracil, which interferes with thymidylate synthesis and RNA processing in dividing cells.
Diarrhoea, hand–foot syndrome, mouth sores, nausea and fatigue can occur. Severe early toxicity, dehydration, chest pain or significant bleeding needs prompt assessment.
DPD deficiency can cause life-threatening fluoropyrimidine toxicity. Kidney function influences dose and suitability. Warfarin and phenytoin interactions require close monitoring. Stop treatment and contact the oncology team for significant diarrhoea or inability to maintain fluids.
An oral fluoropyrimidine can control a susceptible tumour and contribute to adjuvant, chemoradiotherapy or advanced-disease treatment.
It is designed for dispersion in water. The preparation method differs even though the active ingredient and clinical effects are the same.
These can be signs of hand–foot syndrome. Stop the tablets and contact the oncology team if the symptoms are painful or interfere with normal activities. Avoid friction and heat on the affected skin while the symptoms are assessed.
Prepare and drink the dose promptly rather than keeping a mixture for a later administration.
DPD helps break down fluorouracil. Low activity can cause unexpectedly severe toxicity even during the first cycle.
Fluoropyrimidine: an anticancer class related to fluorouracil. DPD: an enzyme involved in fluorouracil breakdown. Hand–foot syndrome: painful skin toxicity affecting palms or soles. Dispersible tablet: a tablet designed to break up in water before administration.; AR: Capecitabine 1000mg أقراص قابلة للتشتت; FR: Capecitabine 1000mg comprimés dispersibles; PT: Capecitabine 1000mg comprimidos dispersíveis; ES: Capecitabine 1000mg comprimidos dispersables; RU: Capecitabine 1000mg диспергируемые таблетки; ID: Capecitabine 1000mg tablet dispersibel; VI: Capecitabine 1000mg viên nén phân tán; MS: Capecitabine 1000mg tablet boleh larut serak; TL: Capecitabine 1000mg mga tabletang natutunaw sa tubig; ZH-SG: Capecitabine 1000mg 分散片
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Capecitabine 1000mg Dispersible Tablets