Cabozantinib 40mg Tablets

Cabozantinib 40mg is a multikinase-inhibitor tablet for selected advanced cancers, including renal-cell carcinoma, previously treated hepatocellular carcinoma and certain differentiated thyroid cancers.
Take on an empty stomach, at least 1 hour before or 2 hours after food. Swallow the tablet whole and avoid grapefruit. If the next dose is due within 12 hours, skip a missed dose.
Cabozantinib inhibits MET, VEGF receptors, AXL and other kinases involved in tumour growth, invasion and angiogenesis.
Diarrhoea, fatigue, reduced appetite, mouth soreness, hypertension and hand–foot skin reactions can occur. Severe bleeding, fistula, thrombosis or gastrointestinal perforation are serious risks.
Blood pressure, urine protein, liver function and thyroid function require monitoring as appropriate. Dental care and treatment interruptions around surgery need planning because of jaw and wound-healing risks.
Blocking several tumour-growth pathways can delay progression in a responsive disease.
No. The formulations have different exposure and clinical contexts and are not substituted milligram for milligram.
A hand–foot reaction can worsen and interfere with walking or hand use. Early management may prevent interruption.
Some renal-cell regimens combine it with nivolumab. Combination-specific monitoring and doses are required.
Jaw osteonecrosis and impaired healing are concerns, so invasive dental treatment needs coordination.
MET and AXL: receptor kinases involved in cell growth and invasion. Hand–foot reaction: painful skin changes on palms or soles. Fistula: an abnormal passage between tissues.; AR: Cabozantinib 40mg أقراص; FR: Cabozantinib 40mg comprimés; PT: Cabozantinib 40mg comprimidos; ES: Cabozantinib 40mg comprimidos; RU: Cabozantinib 40mg таблетки; ID: Cabozantinib 40mg tablet; VI: Cabozantinib 40mg viên nén; MS: Cabozantinib 40mg tablet; TL: Cabozantinib 40mg mga tableta; ZH-SG: Cabozantinib 40mg 片剂
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Cabozantinib 40mg Tablets