Bicalutamide 50mg Tablets$90.00
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Bicalutamide 50mg Tablets
SKU GME1360Oncology Care
Product Introduction
Bicalutamide 50mg is a non-steroidal antiandrogen used with continued testosterone-suppressing treatment in appropriate prostate-cancer regimens.
How to use
Swallow with water once daily at a consistent time, with or without food. Maintain the accompanying GnRH treatment unless surgical castration has already been performed. Do not double a missed daily dose.
How it works
Bicalutamide blocks androgen receptors, reducing the growth signal from testosterone and related androgens in prostate-cancer cells.
Side effects
Hot flushes, breast tenderness or enlargement, reduced libido, fatigue and gastrointestinal symptoms can occur. Jaundice or persistent upper abdominal pain needs assessment.
Important information
Liver tests are important, particularly early in treatment. Warfarin can have an increased anticoagulant effect. The 50mg combination regimen is distinct from higher-dose monotherapy approaches.
Uses
- Prostate cancer with an appropriate GnRH-based or surgical androgen-deprivation regimen.
Benefits
Receptor blockade adds to testosterone suppression and can reduce androgen stimulation of susceptible prostate-cancer cells.
Does it stop testosterone production by itself?
Its main action is receptor blockade. The accompanying GnRH treatment or surgery suppresses production.
Why can it be started around a GnRH agonist injection?
An antiandrogen may help limit symptoms caused by the initial testosterone flare from an agonist.
Can it affect INR testing?
Yes. Warfarin response can increase, so INR needs closer monitoring when treatment changes.
Can the accompanying hormone injections affect my blood sugar?
GnRH agonist injections used with bicalutamide can reduce glucose tolerance. Blood sugar may need closer monitoring, especially if you already have diabetes or glucose control changes after treatment starts.
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