Azacitidine 200mg Tablets$190.00
1–9 boxes
$190.00 each
10–24 boxes
8% off
25+ boxes
10% off
Azacitidine 200mg Tablets
SKU GME1357Oncology Care
Product Introduction
Azacitidine 200mg is an oral hypomethylating anticancer medicine used for continued treatment of selected adults with acute myeloid leukaemia after remission. It has a different treatment role and exposure profile from injectable azacitidine.
How to use
Swallow tablets whole, with or without food, at a consistent time on the scheduled treatment days. Do not cut, crush or chew.
How it works
Azacitidine is incorporated into DNA and RNA and inhibits methyltransferase activity, altering abnormal gene regulation and impairing survival of susceptible malignant cells.
Side effects
Nausea, vomiting, diarrhoea, constipation, fatigue, neutropenia and low platelets can occur. Fever or unusual bleeding needs prompt assessment.
Important information
Follow the cycle calendar carefully because treatment days and rest days are deliberate. Blood counts guide interruptions or adjustments.
Uses
- Continued treatment of selected adults with AML in first remission after intensive induction when further intensive curative treatment cannot be completed.
Benefits
Prolonging disease control after remission can delay relapse in patients who match the established oral-maintenance treatment setting.
Can the tablets replace a 100mg azacitidine injection?
No. Their pharmacokinetics, indications and dosing schedules differ despite the same ingredient name.
Why is an anti-sickness medicine taken before oral azacitidine?
An antiemetic taken 30 minutes beforehand helps prevent nausea and vomiting, particularly during the first two cycles. The preventive medicine may be stopped after those cycles if nausea and vomiting have not occurred.
Why are there days without tablets?
The treatment and rest periods are part of the maintenance cycle and allow recovery from toxicity.
What if I miss or vomit an oral azacitidine dose?
Take a missed tablet as soon as remembered on the same day, then return to the regular time the next day. If you vomit after a dose, do not repeat it. Never take two doses on the same day to make up for a missed one.
AML: acute myeloid leukaemia. Remission: a substantial reduction in detectable disease. Hypomethylating agent: a medicine that reduces DNA methylation.; AR: Azacitidine 200mg أقراص; FR: Azacitidine 200mg comprimés; PT: Azacitidine 200mg comprimidos; ES: Azacitidine 200mg comprimidos; RU: Azacitidine 200mg таблетки; ID: Azacitidine 200mg tablet; VI: Azacitidine 200mg viên nén; MS: Azacitidine 200mg tablet; TL: Azacitidine 200mg mga tableta; ZH-SG: Azacitidine 200mg 片剂