Afatinib 40mg Tablets

Product Introduction

Afatinib 40mg is a targeted treatment for non-small cell lung cancer with susceptible EGFR mutations. It is also used in a defined setting for squamous lung cancer that has progressed after platinum-based chemotherapy.

How to use

Take the tablet once daily on an empty stomach, at least one hour before or two hours after a meal. Swallow with water and use a consistent daily time.

How it works

Afatinib irreversibly inhibits signalling through EGFR and related ErbB-family receptors. Blocking these growth signals slows multiplication of susceptible lung-cancer cells.

Side effects

Diarrhoea, acne-like rash, mouth sores, dry skin, reduced appetite and nail inflammation are common. Severe dehydration, liver injury, lung inflammation and corneal inflammation can occur. New breathing difficulty, jaundice or eye pain needs prompt assessment.

Important information

Begin the supplied diarrhoea-treatment plan at the first loose stools and maintain fluid intake; persistent or severe symptoms may require treatment interruption. Sun protection helps limit skin reactions. Kidney function and interacting P-glycoprotein medicines can affect exposure and dosing.