Abiraterone Acetate 250mg Tablets$325.00
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Abiraterone Acetate 250mg Tablets
SKU GME1355Oncology Care
Product Introduction
Abiraterone Acetate 250mg is a hormone-synthesis inhibitor used with a corticosteroid for advanced prostate cancer. It forms part of treatment alongside continued medical or surgical testosterone suppression.
How to use
Take conventional tablets on an empty stomach: no food for at least 2 hours before and 1 hour after the dose. Swallow whole with water. Take the accompanying prednisone or prednisolone on its scheduled plan. Food instructions for other abiraterone formulations do not replace this fasting interval.
How it works
Abiraterone acetate is converted to abiraterone, which inhibits CYP17 and reduces androgen synthesis in the testes, adrenal glands and tumour tissue.
Side effects
Fluid retention, high blood pressure, low potassium, fatigue and liver-enzyme increases can occur. Severe weakness, palpitations, jaundice or increasing breathlessness needs assessment.
Important information
Blood pressure, potassium and fluid status are checked regularly, with closer liver monitoring early in treatment. Do not abruptly stop the accompanying steroid. Strong enzyme inducers and some heart or psychiatric medicines can interact.
Uses
- Selected metastatic castration-resistant or high-risk metastatic castration-sensitive prostate cancer with an appropriate corticosteroid and androgen-deprivation regimen.
Benefits
Suppressing androgen production beyond the testes adds another level of hormonal control and can delay disease progression in eligible advanced prostate cancer.
Why is a corticosteroid given with abiraterone?
CYP17 inhibition can increase mineralocorticoid effects, causing hypertension, fluid retention and low potassium. Prednisone or prednisolone helps limit this imbalance.
Why is the empty-stomach interval strict?
Food can markedly increase exposure to conventional tablets, making absorption and adverse effects less predictable.
Should I double a dose missed yesterday?
No. Resume the usual daily dose the following day. Several missed days of abiraterone or the steroid require a specific restart plan.
Why tell the team about surgery or a serious infection?
The body normally increases cortisol during stress. Temporary steroid adjustment may be needed because treatment limits this response.
CYP17: an enzyme involved in androgen synthesis. Mineralocorticoid effect: salt- and water-retaining hormonal activity. Castration-resistant: progressing despite castrate testosterone levels.; AR: Abiraterone Acetate 250mg أقراص; FR: Abiraterone Acetate 250mg comprimés; PT: Abiraterone Acetate 250mg comprimidos; ES: Abiraterone Acetate 250mg comprimidos; RU: Abiraterone Acetate 250mg таблетки; ID: Abiraterone Acetate 250mg tablet; VI: Abiraterone Acetate 250mg viên nén; MS: Abiraterone Acetate 250mg tablet; TL: Abiraterone Acetate 250mg mga tableta; ZH-SG: Abiraterone Acetate 250mg 片剂