Azathioprine 50mg Tablets$66.00
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$66.00 each
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Azathioprine 50mg Tablets
SKU GME659Product Introduction
Azathioprine is an immunosuppressant used in transplant care and selected autoimmune disorders. Its effect develops gradually and depends on monitoring for bone-marrow and liver toxicity.
How to use
Take the prescribed schedule consistently; food can improve nausea when the clinician permits. Do not change the dose or add allopurinol or febuxostat without a specialist medication review.
How it works
Conversion to thiopurine metabolites interferes with purine metabolism and lymphocyte proliferation, reducing immune activity.
Side effects
Nausea, low blood-cell counts, infections, liver-test abnormalities or pancreatitis can occur.
Important information
Blood counts and liver tests are essential; TPMT and NUDT15 status may affect susceptibility to severe toxicity. Protect skin from excessive ultraviolet exposure.
Uses
- Transplant-rejection prevention
- selected autoimmune or inflammatory disorders
Benefits
Reduces unwanted immune activity and may lessen reliance on corticosteroids in appropriate conditions.
Why are frequent blood tests needed?
Low white cells or platelets can occur before obvious symptoms.
Can allopurinol or febuxostat be added freely?
No. These can greatly increase thiopurine toxicity and need specialist adjustment or avoidance.
Does genetic testing replace blood-count monitoring?
No. TPMT or NUDT15 assessment does not remove the need for ongoing blood tests.
What infection symptoms should I report?
Fever, persistent sore throat or unusual infections need prompt advice.
Can unexplained bruising matter?
Yes. It can indicate reduced platelets or other marrow toxicity.
Does it work immediately for an autoimmune flare?
No. Response often develops over weeks to months.
Can I receive live vaccines?
Vaccination needs review because live vaccines are generally avoided during significant immunosuppression.
Why is sun protection discussed?
Long-term immunosuppression can increase skin-cancer risk.
Thiopurine: the drug family containing azathioprine. TPMT: an enzyme affecting thiopurine metabolism. NUDT15: a gene affecting susceptibility to thiopurine toxicity., AR: Azathioprine أقراص, FR: Azathioprine comprimés, PT: Azathioprine comprimidos, ES: Azathioprine comprimidos, RU: Azathioprine таблетки, ID: Azathioprine, VI: Azathioprine viên nén, MS: Azathioprine, TL: Azathioprine tableta, ZH-SG: Azathioprine 片剂