Sirolimus 1mg Tablets

Product Introduction

Sirolimus 1mg is an oral immunosuppressant used mainly to help prevent kidney-transplant rejection when sirolimus is part of a specialist transplant regimen. It inhibits the mTOR pathway, reducing T-cell activation and proliferation so the immune system is less likely to attack the transplanted organ.

How to use

Take Sirolimus 1mg exactly as prescribed at the same time each day, consistently with or without food. Do not change dose or miss doses without transplant-team advice. Blood-level monitoring may be required.

How it works

Sirolimus inhibits mTOR signaling, reducing lymphocyte activation and proliferation involved in transplant rejection.

Common side effects

Possible effects include edema, high lipids, high blood pressure, abdominal pain, diarrhea, headache, fever, urinary infection, anemia, nausea, joint pain, low platelets, acne, and mouth ulcers. Serious concerns include infection, lymphoma or skin cancer, pneumonitis, impaired wound healing, kidney problems, proteinuria, and severe allergy.

Important information

Review transplant type, infection risk, vaccination plan, skin-cancer protection, wound healing or upcoming surgery, lipid levels, kidney function, urine protein, blood counts, pregnancy, breastfeeding, cyclosporine/tacrolimus, azoles, macrolides, rifampicin, anticonvulsants, grapefruit, and cannabidiol.