Azathioprine 25mg Tablets$45.00
1–9 boxes
$45.00 each
10–24 boxes
8% off
25+ boxes
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Azathioprine 25mg Tablets
SKU GME1025Product Introduction
Azathioprine 25mg is an immunosuppressant used with other medicines to help prevent rejection of a transplanted organ. It is also used for rheumatoid arthritis and selected autoimmune conditions, including inflammatory bowel disease, when longer-term immune control is needed. Its effect builds gradually rather than providing immediate symptom relief.
How to use
Swallow the tablet whole with water at a consistent time. It may be taken with or without food; keeping the relationship to meals consistent is helpful, and food can reduce nausea. Keep milk and dairy products away from the dose: avoid them during the hour before and the two hours after taking the tablet.
How it works
Azathioprine is converted to mercaptopurine and active thiopurine metabolites. These interfere with purine-dependent nucleic-acid synthesis and immune-cell activity, reducing the immune response responsible for transplant rejection and some autoimmune inflammation.
Side effects
Nausea, reduced appetite, lower blood-cell counts, infections and abnormal liver tests can occur. Fever, a persistent sore throat, unusual bruising, jaundice or severe upper-abdominal pain need prompt assessment for infection, marrow suppression, liver injury or pancreatitis.
Important information
Full blood counts and liver tests are needed during treatment; normal TPMT or NUDT15 results do not replace these tests. Tell your doctor about kidney or liver disease, previous cancer and plans for pregnancy. Immunosuppression increases infection and some cancer risks, including skin cancer. Use sun protection and discuss live vaccines before receiving them.
Uses
- Prevention of organ-transplant rejection
- rheumatoid arthritis and selected autoimmune or inflammatory conditions, including inflammatory bowel disease.
Benefits
Helps control immune-driven tissue injury and can reduce reliance on corticosteroids in some treatment plans. In transplant care it helps protect the donated organ from immune rejection.
How long does Azathioprine 25mg take to help an autoimmune condition?
Improvement commonly takes several weeks and can take a few months. Other medicines may be continued while the immunosuppressive effect develops; a lack of immediate relief is not a reason to increase the dose independently.
Why do TPMT and NUDT15 results matter?
Reduced activity of these enzymes can allow active thiopurine metabolites to accumulate, increasing the risk of severe blood-cell suppression. The findings help determine whether a lower dose or an alternative treatment is needed.
Can azathioprine be taken with allopurinol or febuxostat?
Both can greatly increase thiopurine toxicity. Allopurinol combinations require a deliberately reduced azathioprine regimen with close blood monitoring, while febuxostat is generally avoided. Do not add either gout medicine without changing the treatment plan.
Can I stop it after my transplant has been stable?
Stopping immunosuppression can allow rejection even when the transplanted organ has been working well. Any reduction is coordinated with the transplant team and the other medicines protecting the graft.
What should I do after contact with chickenpox or shingles?
Contact the treatment team promptly if you have been exposed and are not known to be immune. Immunosuppression can make these infections more serious, and preventive treatment may be time-sensitive.
Immunosuppressant: a medicine that reduces immune-system activity; Graft rejection: immune attack on a transplanted organ; Thiopurine: a drug family that interferes with purine-dependent cell processes; TPMT and NUDT15: enzymes whose activity affects thiopurine toxicity risk; Myelosuppression: reduced production of blood cells in bone marrow; AR: Azathioprine 25mg أقراص; FR: Azathioprine 25mg comprimés; PT: Azathioprine 25mg comprimidos; ES: Azathioprine 25mg comprimidos; RU: Azathioprine 25mg таблетки; ID: Azathioprine 25mg tablet; VI: Azathioprine 25mg viên nén; MS: Azathioprine 25mg tablet; TL: Azathioprine 25mg tableta; ZH-SG: Azathioprine 25mg 片剂