Sodium Valproate 500mg Gastro-resistant Tablets$62.00
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Sodium Valproate 500mg Gastro-resistant Tablets
SKU GME813Product Introduction
Sodium Valproate 500mg is a broad-spectrum anti-seizure medicine used in epilepsy. Sodium valproate is also used in selected bipolar treatment plans, depending on the clinical indication and formulation.
How to use
Take with or after food to reduce stomach irritation and keep dose times consistent. Swallow a coated tablet whole. Do not stop abruptly because seizures can recur or worsen; changes require a gradual treatment plan.
How it works
Valproate increases inhibitory GABA activity and influences voltage-sensitive ion channels. These effects reduce excessive electrical activity in the brain.
Side effects
Nausea, tremor, weight gain, hair thinning, sleepiness and easy bruising can occur. Persistent vomiting, severe abdominal pain, jaundice, unusual bleeding or marked confusion require urgent assessment.
Important information
Valproate can cause serious fetal malformations and developmental harm, so pregnancy prevention and pre-pregnancy treatment planning are essential. Liver disease, urea-cycle disorders and some mitochondrial disorders can make it unsuitable. Liver function and blood counts are monitored.
Uses
- Epilepsy
- selected bipolar-disorder treatment regimens.
Benefits
Helps control several seizure types and can stabilise manic symptoms when valproate is an appropriate choice.
Can Sodium Valproate 500mg be stopped when seizures are controlled?
Abrupt withdrawal can provoke recurrent seizures or status epilepticus. Any withdrawal needs a planned gradual approach.
Why are liver tests and platelet counts checked?
Valproate can affect the liver and reduce platelets, increasing bleeding risk even before obvious symptoms appear.
Does it cause weight gain?
Weight gain can occur. Tracking weight helps identify an emerging problem rather than assuming it is unavoidable.
What does severe abdominal pain with vomiting suggest?
It can be a warning sign of pancreatitis, which needs urgent assessment.
Why is pregnancy planning important?
Fetal exposure carries significant structural and neurodevelopmental risks. Treatment must be planned before conception rather than stopped suddenly during pregnancy.
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