Sitagliptin 50mg + Metformin 1000mg + Glimepiride 2mg Tablets

Product Introduction

Sitagliptin 50mg + Metformin 1000mg + Glimepride 2mg combines sitagliptin, glimepiride, and metformin for adults with type 2 diabetes for a three-drug oral regimen treatment. It is intended for type 2 diabetes, not type 1 diabetes or diabetic ketoacidosis. Patients should know low-glucose symptoms such as sweating, shaking, hunger, fast heartbeat, confusion, and unusual sleepiness, and should carry fast-acting sugar if advised.

How to use

Take Sitagliptin 50mg + Metformin 1000mg + Glimepride 2mg as prescribed, usually with meals. Do not skip meals after dosing. Monitor glucose as instructed and know how to treat low blood sugar.

How it works

Sitagliptin supports incretin signaling, glimepiride increases insulin release, and metformin reduces hepatic glucose production and improves insulin sensitivity.

Common side effects

Possible effects include low blood sugar, nausea, diarrhea, abdominal discomfort, headache, weight gain, and metallic taste. Serious concerns include severe hypoglycemia, lactic acidosis, pancreatitis, allergic swelling, severe joint pain, bullous pemphigoid, kidney problems, and heart-failure symptoms.

Important information

Review eGFR, meal pattern, hypoglycemia history, older age, alcohol use, liver disease, heart failure, dehydration, severe infection, contrast imaging, surgery, pancreatitis history, pregnancy, breastfeeding, and other diabetes medicines.