Simvastatin 10mg Tablets$51.00
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$51.00 each
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Simvastatin 10mg Tablets
SKU GME819Product Introduction
Simvastatin 10mg is a statin used to lower LDL cholesterol and reduce cardiovascular risk in appropriate patients. It is used alongside dietary measures for raised cholesterol and some mixed lipid disorders.
How to use
Take in the evening, with or without food, because cholesterol synthesis is more active overnight. Continue lipid testing to assess the response. Do not increase the dose or combine it with another statin to compensate for a high cholesterol result.
How it works
Simvastatin inhibits HMG-CoA reductase in the liver, reducing cholesterol synthesis and increasing removal of LDL particles from the blood.
Side effects
Headache, abdominal discomfort and muscle aches may occur. Unexplained severe muscle pain or weakness, dark urine or jaundice requires prompt assessment.
Important information
Grapefruit and strong CYP3A4 inhibitors can markedly increase simvastatin exposure. Some heart medicines require a lower simvastatin maximum. Active liver disease, pregnancy and breastfeeding materially affect suitability. Muscle risk increases with certain fibrates and interacting antibiotics.
Uses
- Hypercholesterolaemia
- selected mixed dyslipidaemia
- cardiovascular risk reduction.
Benefits
Lowers atherogenic cholesterol and can reduce future cardiovascular events in patients for whom statin therapy is indicated.
Why is Simvastatin 10mg taken in the evening?
Simvastatin is relatively short-acting, and evening dosing better overlaps the body's overnight cholesterol production.
Can grapefruit juice be taken with it?
Grapefruit can inhibit intestinal metabolism and raise simvastatin concentrations, increasing muscle toxicity risk.
Do muscle aches always mean serious injury?
Not always, but new unexplained pain or weakness needs assessment, particularly with dark urine or illness.
Can treatment stop when cholesterol improves?
Cholesterol often rises again after stopping. A good result usually reflects the ongoing effect of treatment and lifestyle measures.
Will it treat chest pain immediately?
No. Its benefit is long-term lipid and risk management, not relief of an acute cardiac symptom.
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