Selegiline 5mg Tablets

Product Introduction

Selegiline 5mg is a monoamine oxidase-B inhibitor used in Parkinson's disease, often alongside levodopa. It helps prolong dopamine activity and can reduce periods when Parkinson symptoms re-emerge between levodopa doses.

How to use

Take oral doses in the morning or at breakfast and lunch when divided, avoiding late-evening use that can disturb sleep. Adding it to levodopa may require adjustment of the levodopa regimen if dyskinesia or other dopaminergic effects increase.

How it works

Selegiline inhibits MAO-B, an enzyme that breaks down dopamine in the brain. This prolongs dopamine availability and strengthens the symptomatic effect of dopaminergic treatment.

Side effects

Insomnia, dizziness, nausea, postural hypotension, hallucinations and involuntary movements may occur. Severe headache, chest pain or signs of serotonin toxicity need urgent assessment.

Important information

MAO-inhibitor interactions are important even at Parkinson doses. SSRIs, SNRIs, tramadol, pethidine, dextromethorphan and sympathomimetic decongestants can cause serious reactions. Do not exceed the intended oral dose, since selectivity decreases at higher exposure.