Rosuvastatin 20mg + Clopidogrel 75mg Capsules

Product Introduction

Rosuvastatin 20mg + Clopidogrel 75mg combines a statin with an antiplatelet medicine for patients who need both cholesterol reduction and antiplatelet treatment. It is used in selected atherosclerotic cardiovascular disease regimens.

How to use

Take the capsule with or without food at a consistent time and swallow it whole with water. Keep any planned interruption coordinated with the cardiovascular team, particularly after coronary intervention. Do not replace it with a statin-only tablet by mistake.

How it works

Rosuvastatin lowers LDL cholesterol through hepatic HMG-CoA reductase inhibition. Clopidogrel is converted to an active metabolite that irreversibly blocks platelet P2Y12 receptors and reduces aggregation.

Side effects

Bruising, nosebleeds, indigestion, diarrhoea and muscle aches may occur. Persistent bleeding, black stools, jaundice or severe muscle weakness needs prompt assessment.

Important information

Other antiplatelets, anticoagulants and NSAIDs increase bleeding risk. Omeprazole and esomeprazole can reduce clopidogrel activation. Liver disease, kidney impairment and previous bleeding are important when assessing the combination.