Pirfenidone 200mg Tablets

Pirfenidone 200mg is an antifibrotic medicine used for idiopathic pulmonary fibrosis. It helps slow progression of lung scarring and the associated decline in lung function; it does not remove existing scar tissue.
Take with food to improve tolerability. Treatment is introduced gradually rather than starting at the full maintenance amount. A substantial interruption may require re-titration. Liver tests are performed before and during treatment.
Pirfenidone has antifibrotic and anti-inflammatory effects, reducing signalling and cellular activity involved in excess collagen production and fibrotic tissue formation.
Nausea, reduced appetite, indigestion, diarrhoea, fatigue, rash and photosensitivity can occur. Jaundice, dark urine or a severe skin reaction requires prompt assessment.
Use protective clothing and high-factor sunscreen because sunlight can trigger significant skin reactions. Smoking can reduce pirfenidone exposure. Fluvoxamine and ciprofloxacin can increase levels. Kidney or liver impairment can affect suitability.
Can slow functional deterioration from progressive pulmonary fibrosis, helping preserve lung function for longer.
No. Its role is to slow progression, not dissolve established fibrosis.
Not necessarily. Benefit is assessed through longer-term symptoms and lung-function trends rather than rapid bronchodilation.
Taking it with meals reduces nausea and other gastrointestinal effects, improving tolerability.
Yes. Smoking induces metabolism and can reduce pirfenidone exposure.
A sufficiently long interruption can require another gradual increase to reduce adverse effects; the restart depends on the length of the gap.
Antifibrotic: reducing processes that form scar tissue. IPF: idiopathic pulmonary fibrosis. Collagen: a structural protein that accumulates in fibrosis. FVC: forced vital capacity, a lung-function measurement; AR: Pirfenidone 200mg أقراص; FR: Pirfenidone 200mg comprimés; PT: Pirfenidone 200mg comprimidos; ES: Pirfenidone 200mg comprimidos; RU: Pirfenidone 200mg таблетки; ID: Pirfenidone 200mg tablet; VI: Pirfenidone 200mg viên nén; MS: Pirfenidone 200mg tablet; TL: Pirfenidone 200mg tableta; ZH-SG: Pirfenidone 200mg 片剂
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Pirfenidone 200mg Tablets