Midodrine 5mg Tablets

Product Introduction

Midodrine 5mg is an alpha-1 agonist used for symptomatic orthostatic hypotension. It raises standing blood pressure to reduce dizziness or faintness associated with inadequate vascular tone.

How to use

Take during waking hours when you expect to be upright. Keep the last dose at least four hours before bedtime and avoid taking a dose before prolonged lying down. Measure sitting, standing and lying blood pressure as part of treatment assessment.

How it works

Midodrine is converted to desglymidodrine, which stimulates peripheral alpha-1 receptors. Constriction of veins and arteries increases vascular tone and blood pressure.

Side effects

Goosebumps, scalp tingling, itching, chills and urinary difficulty may occur. A pounding headache, blurred vision or chest discomfort while lying down can indicate excessive supine blood pressure.

Important information

Supine hypertension is a major risk. Urinary retention, severe heart disease and significant kidney disease are important before treatment. Other vasoconstrictors, including decongestants, can raise pressure further. Benefit should be judged by upright symptoms as well as numbers.