Lopinavir 200mg + Ritonavir 50mg Tablets$84.00
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Lopinavir 200mg + Ritonavir 50mg Tablets
SKU GME1109Antiviral
Product Introduction
Lopinavir 200mg + Ritonavir 50mg is a boosted protease-inhibitor combination used with other antiretroviral medicines for HIV-1 infection. It helps control viral replication as one component of a complete HIV regimen.
How to use
Swallow the tablets whole with water, with or without food. Taking them with a meal may improve stomach tolerance. Adult treatment is commonly divided into two daily doses; the number of tablets depends on the HIV regimen. Do not crush the tablets or substitute an oral-solution volume for a tablet dose.
How it works
Lopinavir inhibits HIV protease, preventing newly formed viral particles from maturing into infectious virus. Ritonavir slows lopinavir breakdown through CYP3A inhibition, maintaining effective lopinavir concentrations.
Side effects
Diarrhoea, nausea, vomiting, abdominal discomfort and increases in cholesterol or triglycerides can occur. Pancreatitis, liver injury and heart-rhythm changes are more serious. Severe upper-abdominal pain, jaundice or fainting requires prompt assessment.
Important information
Ritonavir creates important interactions, including with simvastatin, some rhythm medicines, sedatives and steroid preparations. Blood fats, glucose and liver function are monitored. Hepatitis B or C, diabetes, pancreatitis history and conduction problems affect the treatment plan.
Uses
- HIV-1 infection in combination with other appropriate antiretroviral medicines.
Benefits
The boosted combination maintains protease inhibition through the dosing interval and can contribute to durable HIV suppression. Controlling viral replication helps protect immune function and reduce HIV-related illness.
Why is ritonavir included at a smaller dose?
Its main role in this combination is pharmacokinetic boosting: it slows the breakdown of lopinavir rather than serving as a separate full-dose treatment.
Can I use this tablet as the whole HIV regimen?
No. Lopinavir/ritonavir is normally combined with other active HIV medicines. The low-dose ritonavir component does not make it a complete two-drug regimen.
Why can an inhaled or nasal steroid cause an interaction?
Ritonavir can greatly raise exposure to some steroids, including fluticasone, even when they are not swallowed. This can cause steroid excess and adrenal suppression.
Does a rise in triglycerides mean the HIV treatment is failing?
Not necessarily. It can be a metabolic effect of therapy. Viral-load results assess HIV control, while lipid results guide cardiovascular-risk management.
Protease inhibitor: antiviral blocking viral protein processing. Pharmacokinetic booster: medicine slowing another drug's breakdown. CYP3A: enzyme involved in many drug interactions. Triglycerides: fats measured in the blood. Adrenal suppression: reduced natural cortisol production.; AR: Lopinavir 200mg + Ritonavir 50mg أقراص; FR: Lopinavir 200mg + Ritonavir 50mg comprimés; PT: Lopinavir 200mg + Ritonavir 50mg comprimidos; ES: Lopinavir 200mg + Ritonavir 50mg comprimidos; RU: Lopinavir 200mg + Ritonavir 50mg таблетки; ID: Lopinavir 200mg + Ritonavir 50mg tablet; VI: Lopinavir 200mg + Ritonavir 50mg viên nén; MS: Lopinavir 200mg + Ritonavir 50mg tablet; TL: Lopinavir 200mg + Ritonavir 50mg tableta; ZH-SG: Lopinavir 200mg + Ritonavir 50mg 片剂