Leuprolide Acetate 22.5mg Injection

Product Introduction

Leuprolide Acetate 22.5mg is a depot gonadotropin-releasing hormone agonist used for hormone-dependent conditions when leuprolide acetate is prescribed. Depending on patient group and formulation, it may be used for prostate cancer, endometriosis, uterine fibroids, central precocious puberty, or other specialist-directed hormone-suppression indications. Leuprolide first stimulates and then downregulates pituitary GnRH receptors, leading to reduced LH and FSH release and lower sex-hormone production over time. Depot strength usually reflects dosing interval, so 3.75mg, 11.25mg, and 22.5mg products should not be treated as interchangeable.

How to use

Leuprolide Acetate 22.5mg is given as a depot injection by trained healthcare professionals. Keep injections on schedule because missed doses can reduce hormone suppression. Follow disease-specific monitoring.

How it works

Leuprolide initially stimulates and then suppresses pituitary GnRH signaling, reducing LH and FSH and lowering downstream sex-hormone production.

Common side effects

Possible effects include hot flashes, sweating, fatigue, mood changes, headache, injection-site reaction, reduced libido, sexual dysfunction, vaginal dryness or bleeding changes, and bone-density loss with longer use. Serious concerns include symptom flare, depression, seizures, severe allergic reaction, heart or glucose effects, and pituitary apoplexy symptoms.

Important information

Review indication, depot interval, pregnancy status, breastfeeding, unexplained vaginal bleeding, osteoporosis, depression, seizures, diabetes, heart disease, QT risk, prostate cancer urinary/spinal symptoms, and other hormonal medicines.