Letermovir 240mg Tablets$305.00
1–9 boxes
$305.00 each
10–24 boxes
8% off
25+ boxes
10% off
Letermovir 240mg Tablets
SKU GME1435Antiviral
Product Introduction
Letermovir 240mg is an antiviral used to prevent cytomegalovirus infection or disease in selected transplant recipients. Treatment is timed to the period of increased CMV risk after transplantation.
How to use
Swallow the tablets whole once daily, with or without food. The adult dose is reduced when cyclosporine is co-administered. Start and stop dates are tied to the transplant type and period of CMV risk.
How it works
Letermovir inhibits the CMV terminase complex, preventing viral DNA from being processed and packaged into new infectious particles.
Side effects
Nausea, diarrhoea, vomiting, headache and peripheral swelling can occur. Important medicine interactions may increase toxicity or reduce antiviral protection.
Important information
CMV blood monitoring continues during prophylaxis. Cyclosporine, tacrolimus, sirolimus and several statins have important interactions requiring regimen-specific management.
Uses
- CMV prophylaxis in selected haematopoietic stem-cell and kidney-transplant settings.
Benefits
Reduces the risk of clinically significant CMV infection during vulnerable periods after transplantation.
Why might 240mg be selected instead of 480mg?
Cyclosporine increases letermovir exposure, so the standard adult dose is reduced when they are used together.
Does it replace other herpes-virus prevention?
No. It is CMV-specific and does not provide reliable protection against herpes simplex or varicella-zoster viruses.
Why are CMV blood tests needed while I am taking prevention?
Breakthrough infection can still occur and may require a different antiviral treatment strategy.
Is it the usual medicine for established CMV disease?
Its principal role is prophylaxis. Active CMV disease generally requires an antiviral regimen selected for treatment rather than prevention.
CMV: cytomegalovirus. Prophylaxis: treatment used to prevent disease. Terminase complex: viral proteins needed to package CMV DNA.; AR: Letermovir 240mg أقراص; FR: Letermovir 240mg comprimés; PT: Letermovir 240mg comprimidos; ES: Letermovir 240mg comprimidos; RU: Letermovir 240mg таблетки; ID: Letermovir 240mg tablet; VI: Letermovir 240mg viên nén; MS: Letermovir 240mg tablet; TL: Letermovir 240mg mga tableta; ZH-SG: Letermovir 240mg 片剂